Table 2.
Toxicity observed during 142 TCE cycles in 43 evaluable patients
| Grade | Relapsed patients | Newly diagnosed patients | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Cycles | Patients | Cycles | Patients | ||||||
| n | % | n | % | n | % | n | % | ||
| Total number | 120 | 100 | 32 | 100 | 22 | 100 | 11 | 100 | |
| Leukopenia | 3 | 35 | 29 | 7 | 22 | 6 | 27 | 2 | 18 |
| 4 | 81 | 67 | 25 | 78 | 16 | 73 | 9 | 82 | |
| Fever >38.5°C | 62 | 52 | 31 | 97 | 11 | 50 | 8 | 72 | |
| Thrombocytopenia | 3 | 9 | 7 | 0 | 0 | 2 | 9 | 0 | 0 |
| 4 | 100 | 83 | 32 | 100 | 20 | 91 | 11 | 100 | |
| Mucositis | 3 | 2 | 2 | 2 | 6 | 0 | 0 | 0 | 0 |
| 4 | 2 | 2 | 2 | 6 | 0 | 0 | 0 | 0 | |
| Skin toxicity | 3 | 2 | 2 | 2 | 6 | 1 | 5 | 1 | 9 |
| 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Diarrhea/colitis | 3 | 3 | 2 | 3 | 9 | 4 | 18 | 4 | 36 |
| 4 | 2 | 2 | 2 | 6 | 1 | 5 | 1 | 9 | |
| Nausea/emesis | 3 | 5 | 4 | 2 | 6 | 0 | 0 | 0 | 0 |
| 4 | 3 | 2 | 2 | 6 | 0 | 0 | 0 | 0 | |