Table 3.
Correlation between CDX2 expression and clinicopathological factors
| Total | CDX2 (+) | CDX2 (−) | P value | |
|---|---|---|---|---|
| Age (year ± SD) | 57.1 ± 9.9 | 54.5 ± 10.3 | 0.342a | |
| Sex (F/M) | 14/45 | 5/17 | 9/28 | 0.575b |
| Tumor size (cm ± SD) | 5.5 ± 3.7 | 7.2 ± 3.0 | 0.048a | |
| Location | ||||
| Intrahepatic type | 36 | 12 | 24 | 0.431b |
| Extrahepatic type | 23 | 10 | 13 | |
| Histological type | ||||
| Papillary | 22 | 14 | 8 | 0.002b |
| Tubular | 37 | 8 | 29 | |
| Lymph node metastasisc | ||||
| (+) | 25 | 7 | 18 | 0.087b |
| (−) | 23 | 12 | 11 | |
| Distant metastasisd | ||||
| (+) | 13 | 3 | 10 | 0.228e |
| (−) | 43 | 17 | 26 | |
| pERK1/2 | ||||
| (+) | 29 | 13 | 16 | 0.239b |
| (−) | 30 | 9 | 21 | |
aStudent’s t test
b χ 2 independence test
cLymph node metastasis data were not available in 11 cases
dDistant metastasis data were not available in three cases
eFisher’s exact probability test