Fig. 2.

Cases with different LOH patterns. a LOH of D3S3040 in case S25, loss of the lower allele in U1, U2 and T. b LOH of D3S3040 in case S30, loss of the lower allele in U1. c LOH of D3S3040 in case S21, showing loss of the lower allele in U1, U3 and T. Note, U1 is histopathologically normal iodine-unstained tissue. d LOH of D3S3040 in case S29, D3S3040 showing loss of the lower allele in U1 and T, whereas U2 with loss of the upper allele. B blood DNA; N normally iodine-stained mucosa; U iodine-unstained mucosa. T tumor tissue