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. 2007 Aug 14;134(3):307–315. doi: 10.1007/s00432-007-0269-y

Table 4.

Frequency of LOH in specimens of esophagectomy

Pathological diagnosis USL lesions LOH in USL (%) EC (%) LOH in both EC and USL (%*)
Normal* (%) ES (%) BCH (%) mD+MD (%) SD (%)
RPL14 2/15/26 (13) 0/2/8 (0) 0/2/8 (0) 4/12/19 (33) 3/4/8 (75) 8/22/36 (36) 11/22/36 (50) 6/22/36 (55)
D321768 5/23/26 (22) 2/6/8 (33) 0/6/8 (0) 6/15/19 (28) 5/5/8 (100) 14/29/36 (48) 21/29/36 (72) 12/29/36 (57)
D3S3040 7/20/26 (35) 3/5/8 (60) 0/6/8 (0) 3/16/19 (18.8) 5/7/8 (71) 13/29/36 (46) 20/29/36 (69) 11/29/36 (55)
D3S4542 6/22/26 (27) 2/4/8 (50) 0/6/8 (0) 5/14/19 (38) 5/6/8 (83) 14/28/36 (50) 19/28/36 (67) 9/28/36 (47)
D3S3644 3/15/26 (20) 0/3/8 (0) 0/3/8 (0) 3/12/19 (25) 3/4/8 (75) 8/21/36 (40) 16/21/36 (76) 7/21/36 (44)
D9S169 2/22/26 (9) 0/4/8 (0) 0/6/8 (0) 2/14/19 (14.3) 1/6/8 (17) 5/28/36 (18) 19/28/36 (68) 4/28/36 (21)
D13S171 1/12/26 (8.3) 1/4/8 (25) 0/5/8 (0) 2/14/19 (14.3) 1/5/8 (20) 5/21/36 (24) 13/21/36 (62) 3/21/36 (23)
D13S263 2/18/26 (11) 1/6/8 (17) 1/7/8 (14) 3/13/19 (23) 2/5/8 (40) 7/25/36 (28) 12/25/36 (48) 5/25/36 (38)
Total 28/147 (19) 9/34 (26) 1/41 (2.4) 28/110 (25) 24/42 (57) 130/203 (64)

Normal* histopathologically normal esophageal mucosa unstained by iodine, ES esophagitis, BCH basal cell hyperplasia, mD mild dysplasia, MD moderate dysplasia, SD severe dysplasia, EC esophageal cancer, %* = number of case of LOH in both tumor and usl/number of case of LOH in the tumor, USL unstained of logul’s iodine