Table 5.
Frequency of LOH in biopsy specimens from the high-risk population screening
| Pathological diagnosis | Normal* (%) | ES (%) | BCH (%) | mD+MD (%) | SD (%) | Total (%) |
|---|---|---|---|---|---|---|
| D3S1768 | 3/14/16 (21) | 0/2/3 (0) | 1/1/1 (100) | 7/16/19 (50) | 4/6/7 (67) | 15/39/46 (38) |
| RPL14 | 3/11/15 (27) | 0/2/3 (0) | 1/1/2 (100) | 4/12/18 (43) | 2/5/7 (40) | 10/31/45 (32) |
| D3S3040 | 3/15/15 (20) | 2/3/3 (67) | 0/0/1 (0) | 4/14/19 (29) | 2/5/7 (40) | 11/37/45 (30) |
| D3S4542 | 3/12/15 (25) | 1/3/3 (33) | 1/1/2 (100) | 7/15/19 (25) | 3/7/7 (43) | 15/38/46 (39) |
| D3S3644 | 2/8/16 (25) | 2/3/3 (67) | 1/1/1 (100) | 3/11/19 (14) | 3/4/7 (75) | 11/27/46 (41) |
| D13S263 | 4/15/16 (27) | 2/2/3 (100) | 0/2/2 (0) | 4/16/19 (22) | 1/4/7 (25) | 11/39/47 (28) |
| Total | 18/75/93 (24) | 7/15/18 (47) | 4/6/9 (67) | 29/84/113 (35) | 15/31/42 (48) | 73/211/275 (35) |
N* histopathologically normal esophageal mucosa unstained by iodine, ES esophagitis, BCH basal cell hyperplasia, mD mild dysplasia, MD moderate dysplasia, SD severe dysplasia