Table 2.

Univariate and multivariate analysis of overall survival in hepatocellular carcinoma

Variables	Univariate analysis			Multivariate analysis
	HR	95% CI	P value	HR	95% CI	P value
IDO	1.668	1.085–2.565	0.020a	1.804	1.154–2.819	0.010a
Age	0.990	0.644–1.521	0.962
Gender	0.547	0.264–1.133	0.104
Tumor size	1.978	1.275–3.068	0.002a	1.810	1.150–2.848	0.010a
Histologic grade	1.383	0.987–1.937	0.059
Cirrhosis	0.907	0.593–1.387	0.653
HBSAg status	1.384	0.734–2.610	0.315
Serum AFP	2.035	1.326–3.124	0.001a	2.003	1.290–3.111	0.002a
Metastasis	1.753	1.014–3.029	0.044a	1.039	0.567–1.904	0.902
Recurrence	1.582	1.024–2.444	0.039a	1.383	0.866–2.209	0.174

HR Hazard ratio, CI confidence interval

^a P value < 0.05