Table 2.

Multi-drug regimen employed to prevent generation of mediators of anaphylaxis

Prednisone 50 mg PO q	6 h×3 doses beginning the day (10 a.m.; 4 p.m.; 10 p.m.) prior to chemotherapy
Famotidine (Pepcid) 20 mg IV	30 minutes prior to treatment
Dexamethasone 20 mg IV	30 minutes prior to treatment
Diphenhydramine 50 mg IV	30 minutes prior to chemotherapy
Zileuton (Zyflo) 600 mg PO QID	For 5 days prior to chemotherapy
Montelukast sodium (Singulair) 10 mg PO QD HS	For 5 days prior to chemotherapy
Indomethicin 50 mg PO TID	For 1 day (10 a.m.; 4 p.m.; 10 p.m.) prior to chemotherapy
Albuterol sulfate (Volmax) 8 mg PO BID	For 1 day (10 a.m.; 10 p.m.) prior to chemotherapy