Table 2.
Hormonal-metabolic status of endometrial cancer patients with a different value of insulin resistance index
| Parameter | Insulin resistance index <4,8 | Insulin resistance index ≥4,8 | Significance level, Pb |
|---|---|---|---|
| Age, years | 58a (52; 62) | 59 (51;66) | 0,49553 |
| Body mass index kg/m2 | 27,1 (23,8; 30,5) | 32,7 (28,4;34,8) | <0,00001 |
| Waist/hip ratio | 0,83 (0,8; 0,92) | 0,89 (0,84; 0,94) | 0,03386 |
| Body fat, % | 25,49 (21,08; 30,16) | 33,41 (25,285; 40,85) | 0,01153 |
| Glucose, 0 min mmol/l | 5,11 (4,61; 5,61) | 5,99 (5,16; 7,16) | <0,00001 |
| Glucose, 120 min mmol/l | 6,54 (5,41; 7,85) | 8,58 (6,44; 10,43) | 0,00061 |
| Insulin, 0 min μU/l | 9,0 (5,0; 11,9) | 20,1 (18,0; 26,6) | <0,00001 |
| Insulin, 120 min μU/l | 40,1 (24,7; 66,8) | 101,9 (67,5;135,0) | <0,00001 |
| Insulin resistance index | 2,11 (1,19; 4,41) | 5,44 (5,0; 7,46) | <0,00001 |
| C-peptide 0 min, pmol/l | 623,5 (407;679) | 900,0 (756,0; 1230,5) | <0,00001 |
| C-peptide 120 min, pmol/l | 2246,5 ( 1767,0; 3134,0) | 3154,0 (2645,5; 4306,5) | 0,00354 |
| Total cholesterol, mmol/l | 5,62 (4,64; 6,60) | 5,57 (4,59; 6,63) | 0,86629 |
| Triglycerides, mmol/l | 1,46 (1,00; 2,04) | 1,55 (1.27; 2,09) | 0,04985 |
| Total lipoproteins, cond. units | 363,0 (304,0; 474,0) | 473,5 (378,0; 584,0) | 0,00451 |
a Data are presented as medians and 25- and 75-percentiles (in brackets)
b According to Mann Whitney U-criterion (patients in reproductive period vs postmenopausal patients)