Table 3.
Incidence of non-hematologic toxicities during study treatment (by patient and by cycle)
| Patients | Cycles | |||||||
|---|---|---|---|---|---|---|---|---|
| Total | Grade 3/4 | Total | Grade 3/4 | |||||
| n | % | n | % | n | % | n | % | |
| Nausea | 26 | 65.0 | 0 | 0 | 77 | 51.4 | 0 | 0 |
| Vomiting | 18 | 45.0 | 0 | 0 | 37 | 24.7 | 0 | 0 |
| Stomatitis | 20 | 50.0 | 4 | 10.0 | 44 | 29.3 | 6 | 4.0 |
| Diarrhea | 3 | 7.5 | 0 | 0 | 6 | 4.0 | 0 | 0 |
| Asthenia | 16 | 40.0 | 0 | 0 | 43 | 28.7 | 0 | 0 |
| Periph. neuropathy | 23 | 57.5 | 0 | 0 | 60 | 40.0 | 0 | 0 |
| Myalgia | 6 | 15.0 | 0 | 0 | 12 | 8.0 | 0 | 0 |
| Arthralgia | 9 | 22.5 | 0 | 0 | 16 | 10.7 | 0 | 0 |
| Skeletal pain | 15 | 37.5 | 0 | 0 | 40 | 26.7 | 0 | 0 |
| Cardiotoxicity | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Infection | 6 | 15.0 | 0 | 0 | 7 | 4.7 | 0 | 0 |
| Febrile neutropenia | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Fever | 6 | 15.0 | 0 | 0 | 7 | 4.7 | 0 | 0 |