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. 2025 May 25;10(22):22994–23000. doi: 10.1021/acsomega.5c00842

1. Comparative Analysis of Biochemical Markers across the Study Groups,

parameter group A (healthy) group B (nondiabetic cardiac) Group C (diabetic cardiac) p-value
homocysteine (μmol/L) 12.53 ± 1.45 14.75 ± 4.06 16.07 ± 4.71 0.002
TLC (cells/μL) 9290.00 ± 528.72 11015.15 ± 2139.38 12444.44 ± 2014.24 0
ESR (mm/h) 14.06 ± 0.94 29.18 ± 6.13 31.14 ± 6.13 0
cholesterol (mmol/L) 4.94 ± 0.43 5.79 ± 0.56 5.88 ± 0.64 0
triglycerides (mmol/L) 1.51 ± 0.42 2.10 ± 0.44 2.40 ± 0.70 0
HDL (mmol/L) 1.13 ± 0.14 2.66 ± 0.66 1.36 ± 0.44 0
LDL (mmol/L) 2.77 ± 0.29 3.16 ± 0.59 3.11 ± 0.48 0.002
a

The results demonstrate the values as mean values alongside standard deviation (SD). The study subjected 78 healthy participants to Group A, while Group B and Group C received nondiabetic cardiac patients (n = 78) and diabetic cardiac patients (n = 78), respectively. Researchers discovered that all markers generated distinctive variations between study groups based on ANOVA statistical tests with p-values below 0.05. The abbreviations used in this analysis include the following keys: TLC represents total leukocyte count with normal range from 4000 to 11,000 cells/μL and ESR stands for erythrocyte sedimentation rate with normal values below 20 mm/h in males and below 30 mm/h in females while HDL denotes high-density lipoprotein with optimal levels exceeding 1.0 mmol/L in males and 1.3 mmol/L in females and finally LDL corresponds to low-density lipoprotein with a risk-associated target lower than 2.6 mmol/L. The laboratory measured all lipid values from fasting blood draw samples.

b

The results showed a statistically significant difference (p < 0.05) among the three groups for all biochemical markers.