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. 2025 May 25;10(22):22994–23000. doi: 10.1021/acsomega.5c00842

2. Statistical Analysis of Serum Homocysteine Concentration under Normal Limits between 5-15 μmol/L Was Performed against Biochemical Markers,,

  group A (healthy)
group B (nondiabetic cardiac)
group C (diabetic cardiac)
parameter R p r
TLC –0.015 0.936 0.255
ESR 0.099 0.604 0.362*
cholesterol 0.241 0.199 0.012
triglycerides 0.26 0.15 0.01
HDL 0.003 0.986 –0.083
LDL –0.16 0.399 0.063
a

The statistical tests produced significant results at p < 0.05 level through asterisk (*) indicators. The results showed a weak but statistically significant positive relationship between homocysteine levels and ESR values in both cardiac groups (Group B: r = 0.362, p = 0.049; Group C: r = 0.342, p = 0.044) yet no significant correlation existed between homocysteine and lipid parameters across all study groups (p > 0.05). Correlation strength interpretation: r = 0.10-0.29 (weak), 0.30–0.49 (moderate). All abbreviations match Table definitions.

b

A statistically significant correlation (p < 0.05).

c

Group B and Group C exhibited a statistically significant weak positive correlation between homocysteine and ESR (p = 0.049 and p = 0.044, respectively).