Table 3.
Partial correlation analysis between regional11C-DPA713-BPND and plasma leptin concentrationa.
| Correlation coefficients (p value) | |
|---|---|
| Regional11C-DPA713-BPND in Braak 1–3 | |
| Hippocampal and parahippocampal region | 0.52 (0.10) |
| Amygdala | 0.24 (0.48) |
| Lingual area | 0.16 (0.63) |
| Fusiform area | |
| Regional11C-DPA713-BPND in Braak 4 | |
| Insular | 0.83 (0.002)∗ |
| Anterior cingulum | 0.44 (0.18) |
| Middle cingulum | 0.44 (0.17) |
| Posterior cingulum | 0.57 (0.07) |
| Temporal area | 0.27 (0.42) |
Abbreviations: BPND, binding potential; ADAS-J-Cog, Alzheimer's Disease Assessment Scale- Cognitive subscale (Japanese version); CSF, cerebrospinal fluid.
∗p < 0.00625 (0.05/8).
a
Partial correlation analysis with age, sex, ADAS-J cog score, CSF Aβ42/40 ratio values and p-tau 181 concentration was covariated