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. 2025 Jun 12;27:104. doi: 10.1186/s13058-025-02027-4

Table 2.

Characteristics of operated patients

Total
n = 528
Dataset A
N = 459
Dataset B
N = 69
P value
Age, n 0.9722b
 < 40 135 (26.57%) 118 (25.71%) 17 (24.64%)
 40–69 367 (69.51%) 318 (69.28%) 49 (71.01%)
 ≥ 70 26 (4.92%) 23 (5.01%) 3 (4.35%)
Menopausal Status 0.793b
 Premenopause 316 (59.85%) 276 (60.13%) 40 (57.97%)
 Menopause 212 (40.15%) 183 (39.87%) 29 (42.03%)
Surgery, n 528 0.6992b
    SLN biopsy only 242 (45.83%) 212 (46.19%) 30 (43.78%)
    ALND 286 (54.17%) 247 (53.81%) 39 (56.52%)
ALN Ultrasound, n 0.0089
 LN Not reported 273 (51.71%) 249 (54.25%) 24 (34.78%)
 LN Reported 161 (30.49%) 131 (28.54%) 30 (43.48%)
 LN Metastasis suspected 94 (17.80%) 79 (17.21%) 15 (21.74%)
Neoadjuvant Chemotherapy 0.0839b
 Yes 37 (7.01%) 31 (6.75%) 9 (13.04%)
 No 491 (92.99%) 428 (93.25%) 60 (86.96%)
Pathological results, n 0.0011*
 Benign 168 (31.82%) 158 (34.42%) 10 (14.49%)
 Pre-malignant 30 (5.68%) 28 (6.10%) 2 (2.90%)
 Malignant 330 (62.50%) 273 (59.48%) 57 (82.61%)
Molecular Subtypes 0.5565
 Luminal A 78 (23.64%) 68 (24.91%) 10 (17.54%)
 Luminal B 160 (48.48%) 132 (48.35%) 28 (49.12%)
 HER2-enriched 44 (13.33%) 34 (12.45%) 10 (17.54%)
 Tripple-Negative 48 (14.55%) 39 (14.29%) 9 (15.77%)
Histological Subtypes 0.2340
 Invasive ductal carcinoma 292 (88.48%) 242 (88.64%) 50 (87.72%)
 Invasive lobular carcinoma 16 (4.85%) 15 (5.50%) 1 (1.75%)
Other Invasive carcinoma  22 (6.67%) 16 (5.86%) 6 (10.53%)
Lymph Vascular Invasion 0.4266b
 Yes 98 (29.70%) 84 (30.77%) 14 (24.56%)
  No 232 (70.30%) 189 (69.23%) 43 (75.44%)
T stage 0.0656b
 T0(DCIS) 30 (8.33%) 28 (9.30%) 2 (3.39%)
 T1 184 (51.11%) 155 (51.50%) 29 (49.15%)
 T2 129 (35.84%) 101 (33.55%) 28 (47.46%)
 T3 17 (4.72%) 17 (5.65%) 0 (0)
N stage 0.0831b
 N0 138 (41.82%) 117 (42.86%) 21 (36.84%)
 N1 103 (31.21%) 77 (28.20%) 26 (45.62%)
 N2 44 (13.33%) 39 (14.29%) 5 (8.77%)
 N3 45 (13.64%) 40 (14.65%) 5 (8.77%)
ER 0.5216b
 Positive 237 (71.82%) 198 (72.53%) 39 (68.42%)
 Negative 93 (28.18%) 75 (27.47%) 18 (31.58%)
PR 0.7662b
 Positive 203 (61.52%) 169 (61.90%) 34 (59.65%)
 Negative 127 (38.48%) 104 (38.10%) 23 (40.35%)
HER-2 0.0521b
 Positive 95 (28.79%) 81 (29.67%) 14 (24.56%)
 Negative 235 (71.21%) 192 (70.33%) 43 (75.44%)
Ki67(%)a 43.42 ± 23.92 43.25 ± 26.02 44.23 ± 25.67

Data are presented as n (%). Data were analyzed using the χ2 test unless otherwise specified. P values of less than 0.05 were considered statistically significant

SLN Sentinel lymph node, LN Lymph node, ALND Axillary lymph node dissection, DCIS Ductal carcinoma in situ, ER Estrogen receptor, PR Progesterone receptor, HER-2 Human epidermal growth factor receptor 2

aData are means ± SD

bFisher’s extract test