Table 2.

TARGET-NBL stage-4 patients dataset, quantitative characteristics of the numerical features. First event: 0 event, 1 progression, 2 relapse, 3 death. std. dev.: standard deviation. MKI: Mitotic Karyorrhectic Index. Percent Necrosis: percentage of dead tumor cells within the cancerous tissue, which can be an important factor in the pathology and prognosis of the disease. Percent Tumor: percentage of tumor cells present in a biopsy or surgical specimen compared to normal cells. Percent Tumor vs Stroma: percentage of tumor cells to stromal cells within a tumor sample. The stroma is the supportive tissue surrounding the tumor cells, which includes connective tissue, blood vessels, and immune cells. Ploidy Value: number of sets of chromosomes in the tumor cells. Neuroblastoma can be classified as either diploid (normal chromosome number) or aneuploid (abnormal chromosome number). Aneuploid tumors often indicate a more aggressive disease and are associated with poorer outcomes. In contrast, diploid tumors may have a better prognosis. Supenhancer group: 0 ATRX, 1 MES, and 2 MYCN, as defined in [12]. More information on this dataset can be found in [12–14]

Feature	Median	Mean	Range	Std. dev.	#NAs
Age at diagnosis days	1328.000	1618.813	[550, 6021]	1112.958
Event Free Survival Time in Days	709.000	1130.341	[87, 4948]	1030.418
First event	2.000	1.746	[0, 3]	0.842	28
MKI	1.000	1.000	[0, 2]	0.799	18
Overall Survival Time in Days	1330.000	1498.923	[87, 4948]	1050.606
Percent Necrosis	10.000	16.383	[0, 90]	18.583	27
Percent Tumor	80.000	71.098	[5, 97.5]	23.518	25
Percent Tumor vs Stroma	80.000	70.841	[5, 98]	23.076	28
Ploidy Value	1.030	1.218	[1, 3]	0.377
Superenhancer group	0.000	0.681	[0, 2]	0.880
Years from diagnosis to last follow-up	4.000	4.055	[0, 14]	2.911