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. 2025 Jun 13;11(24):eadr1644. doi: 10.1126/sciadv.adr1644

Table 2. Heritability estimates of different brain structures.

Heritability estimates are presented for single brain structures ( h2 ) and for combined regions ( h2 combined) as well as their standard errors (SE and SE combined). Here, numbers in bold are significant after Bonferroni correction for 22 brain structures. For comparison, the estimates from Ge et al. (6) are listed in the last two columns. Italic numbers are nominally significant, and bold ones are significant after false discovery rate correction in (6).

Brain structure h2 SE h2 combined SE combined h2 Ge2016 SE Ge2016
4th ventricle 0.169 3.0 × 10−3 0.169 3.0 × 10−3 0.005 0.208
Left accumbens area 0.134 2.8 × 10−3 0.116 1.9 × 10−3 0.237 0.135
Right accumbens area 0.095 2.4 × 10−3
Left amygdala 0.105 2.5 × 10−3 0.118 1.8 × 10−3
Right amygdala 0.134 2.8 × 10−3
Left caudate 0.296 1.9 × 10−3 0.285 1.4 × 10−3 0.499 0.188
Right caudate 0.273 2.0 × 10−3
Brain stem 0.282 5.4 × 10−3 0.198 1.5 × 10−3 0.452 0.192
Left cerebellum cortex 0.186 2.9 × 10−3
Right cerebellum cortex 0.194 2.8 × 10−3
Left cerebellum white matter 0.195 2.6 × 10−3
Right cerebellum white matter 0.148 2.6 × 10−3
Left hippocampus 0.187 2.6 × 10−3 0.199 1.9 × 10−3 0.347 0.169
Right hippocampus 0.210 2.7 × 10−3
Left pallidum 0.124 2.9 × 10−3 0.122 2.0 × 10−3 0.061 0.117
Right pallidum 0.120 2.8 × 10−3
Left putamen 0.158 2.7 × 10−3 0.183 1.9 × 10−3 0.413 0.148
Right putamen 0.210 2.8 × 10−3
Left thalamus proper 0.134 2.7 × 10−3 0.132 1.9 × 10−3 0.086 0.143
Right thalamus proper 0.130 2.7 × 10−3
Left ventral DC 0.122 2.7 × 10−3 0.146 2.1 × 10−3
Right ventral DC 0.169 3.2 × 10−3