TABLE II. Performance parameters obtained for the 18 kits licensed for use and commercially available in Brazil, as used in this study.
| Kits | SEN % (IC95%) | SPE % (IC95%) | ACC % (IC95%) | PLR | NLR | DOR | K (IC95%) |
| EIABio | 100 (96.6-100) | 86.8 (77.4-92.7) | 94.6 (90.3-97.0) | 7.6 | 0.0001 | 71,226 | 0.89 (0.82-0.95) |
| EIADia | 99.0 (94.8-99.8) | 90.5 (81.7-95.3) | 95.5 (91.5-97.7) | 10.5 | 0.0105 | 994 | 0.91 (0.84-0.97) |
| EIARec | 99.1 (95.1-99.8) | 80.8 (70.7-88.0) | 91.5 (86.7-94.7) | 5.2 | 0.0112 | 462 | 0.82 (0.74-0.90) |
| EIALis | 99.1 (95.0-99.8) | 78.2 (67.8-85.9) | 90.4 (85.4-93.9) | 4.5 | 0.0116 | 391 | 0.80 (0.71-0.89) |
| EIASym | 100 (96.6-100) | 88.5 (79.5-93.8) | 95.2 (91.1-97.5) | 8.7 | 0.0001 | 84,260 | 0.90 (0.84-0.96) |
| EIAEur | 92.9 (86.0-96.5) | 89.5 (80.6-94.6) | 91.4 (86.3-94.7) | 8.8 | 0.0798 | 111 | 0.82 (0.74-0.91) |
| EIAGol | 94.5 (88.5-97.5) | 86.8 (77.4-92.7) | 91.4 (86.4-94.6) | 7.2 | 0.0634 | 113 | 0.82 (0.74-0.90) |
| IHAWie | 93.7 (87.6-96.9) | 70.9 (60.1-79.7) | 84.2 (78.4-88.7) | 3.2 | 0.0890 | 36 | 0.67 (0.56-0.78) |
| IHAGol | 71.2 (62.1-78.8) | 94.9 (87.7-98.0) | 81.1 (74.9-86.0) | 14.1 | 0.3037 | 46 | 0.63 (0.52-0.74) |
| IIFVir | 100 (96.5-100) | 62.1 (50.1-72.8) | 85.5 (79.5-90.0) | 2.6 | 0.0002 | 17,547 | 0.67 (0.55-0.79) |
| IIFCon | 87.4 (79.9-92.3) | 88.6 (79.7-93.9) | 87.9 (82.5-91.8) | 7.7 | 0.1423 | 54 | 0.75 (0.66-0.85) |
| IIFBio | 90.1 (83.1-94.4) | 73.4 (62.8-81.9) | 83.2 (77.2-87.8) | 3.4 | 0.1350 | 25 | 0.65 (0.54-0.76) |
| RDTOns | 92.8 (86.3-96.8) | 87.3 (78.0-93.8) | 90.5 (85.5-93.9) | 7.3 | 0.08 | 89 | 0.80 (0.72-0.78) |
| RDTSdb | 95.5 (89.9-98.5) | 89.9 (81.0-95.5) | 93.2 (88.6-96.0) | 9.43 | 0.05 | 188 | 0.86 (0.78-0.93) |
| RDTWlc | 97.3 (92.3-99.4) | 92.4 (84.2-97.2) | 95.3 (91.2-97.5) | 12.8 | 0.03 | 438 | 0.90 (0.84-0.96) |
| RDTBio | 100 (96.7-100) | 78.5 (68.2-86.1) | 91.1 (86.1-94.3) | 4.65 | <0.001 | 40,469 | 0.81 (0.72-0.90) |
| CMIAAr | 97.3 (92.4-99.1) | 81.4 (69.6-89.3) | 91.8 (86.7-95.0) | 5.2 | 0.03 | 157 | 0.81 (0.72-0.91) |
SEN: sensitivity; SPE: specificity; ACC: accuracy; PLR: positive likelihood ratio; NLR: negative likelihood ratio; DOR: diagnostic odds ratio; k: Cohen’s Kappa index. Note: to determine the performance parameters, the number of samples with indeterminate results was disregarded.