Table 4.

Log-rank analysis performed for EFS and OS for different cutoffs

	Cutoff method	Cutoff value	EFS log-rank (p-value)	OS log-rank (p-value)
SULmax	Median	8.07	0.01a	0.56
	Max Youden	8.54	< 0.01a	0.49
	Maximally selected rank	6.28	< 0.01a	0.44
	Published cutoff [18]	6	0.04a	0.68
SULpeak	Median	6.93	0.03a	0.90
	Max Youden	6.90	0.03a	0.90
	Maximally selected rank	5.46	0.01a	0.84
	Published cutoff [16]	7.98	0.02a	0.64
MTVtotal	Median (cm3)	143.9	0.08	0.64
	Max Youden (cm3)	80.37	0.03a	0.22
	Maximally selected rank (cm3)	38.04	0.06	0.2
	Published cutoff [16] (cm3)	238.1	0.94	0.86
TLGtotal	Median	531.1	0.08	0.69
	Max Youden	193.8	< 0.01a	0.13
	Maximally selected rank	192.0	0.02a	0.17
	Published cutoff [16]	981.97	0.72	0.9

EFS event-free survival, MTV metabolic tumor volume, SUL standardized uptake value lean-body mass corrected, TLG total lesion glycolysis, OS overall survival

^a Indicates significance