Fig. 2.

Squalamine (blue bars) and claramine A1 (orange bars) can prevent biofilm formation (A) and eradicate a 24 h-preformed biofilm upon 2 h (B) or 24 h (C) treatment at different concentrations. The error bars represent the standard error of the means (SEMs) and are the result of the analysis of three independent biological assays. Statistics were achieved by ordinary one-way ANOVA followed by Tukey's multiple-comparison test. Significance was considered at ∗∗∗∗, p < 0.0001; ∗∗∗, p = 0.0001–0.001; ∗∗, p = 0.001–0.01; ∗, p = 0.01–0.05; ns (not significant), p > 0.05.