Why carry out this study?

Diabetes-associated dry eye disease (DED) is the most common ocular surface condition in diabetes mellitus. Delayed diagnosis and intervention, often due to corneal hypoesthesia, can lead to diabetic neurotrophic keratopathy (DNK).

This study used the Michigan Neuropathy Screening Instrument Questionnaire (MNSIQ) to analyze the correlation between peripheral neuropathy symptoms and dry eye signs in patients with type 2 diabetes, highlighting the importance of MNSIQ as an indicator for DED.

What was learned from the study?

The MNSIQ reliably evaluated corneal epithelial integrity, lacrimal functional unit (LFU) function, and corneal nerve density and function in patients with type 2 diabetes-related DED.

Peripheral corneal neuropathy is crucial in diabetic ocular surface complications, highlighting the importance of including the MNSIQ score in routine ophthalmic evaluations.