Table 3.
Comparison of BMI SDS and DHEA-s levels
| Overweight/Obesity | Exaggerated Adrenarche | |||||
|---|---|---|---|---|---|---|
| Yes (n=32) | No (n=72) | p-value | Yes (n=19) | No (n=85) | p-value | |
| Age at evaluation, years (mean, SD) | 6.75±1.26 | 7.33±0.70 | <0.05a | 7.34±0.83 | 7.11±0.97 | 0.334a |
| The age of onset of complaint (mean, SD) | 6.27±1.34 | 6.78±0.94 | 0.110a | 6.74±0.86 | 6.60±1.15 | 0.619a |
| Gestational age, week (mean, SD) | 38.7±1.39 | 38.3±1.64 | 0.252a | 37.6±1.8 | 38.6±1.4 | <0.05a |
| Birth weight, g (mean, SD) | 3031±667 | 2732±536 | 0.080a | 2437±743 | 2910±520 | <0.05a |
| Birth weight SDS (mean, SD) | -0.38±1.43 | -0.95±1.14 | <0.05a | -1.4±1.5 | -0.6±1.1 | <0.05a |
| ∆Weight SDS | 2.31±1.63 | 0.92±1.11 | <0.05a | 2.12±2.15 | 1.17±1.17 | <0.05a |
| Prematurity (n, %) | 4(%12.5) | 11(15.2) | 0.484b | 7(%36.8) | 8(%9.4) | <0.05b |
| SGA (n, %) | 4(%12.5) | 26(%36) | <0.05b | 7(%36.8) | 23(%27) | 0.279b |
| Weight SDS (mean, SD) | 1.96±0.71 | 0.03±0.78 | <0.05a | 0.71±1.34 | 0.60±1.14 | 0.724a |
| Height SDS (mean, SD) | 0.98±0.85 | 0.17±0.99 | <0.05a | 0.42±0.90 | 0.42±1.04 | 0.986a |
| BMI SDS (mean, SD) | 1.84±0.55 | -0.07±0.77 | <0.05a | 0.57±1.40 | 0.49±1.08 | 0.791a |
| Overweight/obesity (>1 SDS) (n, %) | - | - | 6(%31.6) | 26(%30.6) | 0.933b | |
| BA, years (mean, IQR) | 7.5±1.53 | 7.6±0.88 | 0.820a | 8.0±0.79 | 7.5±1.15 | 0.032a |
| BA-CA, years (mean, SD) | 0.81±1.20 | 0.28±0.79 | <0.05a | 0.69±1.14 | 0.39±0.92 | 0.231a |
| DHEA-S (mean, SD) | 88.4±48.4 | 92.3±48.7 | 0.706a | 173.0±42.7 | 72.8±25.1 | <0.005a |
| Exaggerated adrenarche (n, %) | 6(%18.8) | 13(%18.1) | 0.566b | - | - | |
a) Mann-Whitney U-test for independent samples; b) Chi-square. ∆Weight SDS: Weight SDS minus Birth Weight SDS. BMI: Body Mass Index. BA: Bone Age BA-CA: bone age (years, months) minus chronological age (years, months).