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. 2025 Jun 3;16:1507398. doi: 10.3389/fphys.2025.1507398

TABLE 3.

Thermoregulatory (basal, final and delta core body temperature) and performance outcomes for included studies investigating the effects of menstrual cycle phase on performance in hot conditions (k=6).

Study Participant characteristics Basal Tcore (°C) Basal Tsk (°C) Final Tcore (°C) Delta Tcore (°C) Performance test Performance outcome
Hashimoto et al. (2014) V˙ O2max 39.5 ±5.3 mL/kg/min. Physically active (n=2); not physically active (n=4) Elevated in L vs. F (P<0.05) Not reported Elevated in L vs. F (P<0.05) Not reported 90-min cycling (50% V̇O2peak) followed by TT NS
Lei 2017 V˙ O2max 55 ±9 mL/kg/min. Trained cyclists/triathletes (n=10) 0.21 ±0.14 °C higher in ML vs. EF
(P<0.05)
NS 0.23 ±0.28 °C higher in ML vs. EF in hot humid (P<0.05) no difference in hot dry Elevated in EF (1.40 ±0.18) vs. ML (1.23 ±0.27; P<0.05) 30-min cycling TT NS
Wright 2002* V˙ O2peak 51 ±1.9 mL/kg/min. Trained runners Elevated in L (37.7) vs. F (37.42 ±0.28; P<0.05) Not reported NS Elevated in F vs. L (P<0.05) 30-min running TT NS
Zheng et al. (2021) V˙ O2max 46.4 ±7.1 mL/kg/min 0.28 ±0.25 °C higher in ML vs. EF (P<0.05) NS NS NS 20-min fixed-intensity cycling followed by 30-min TT NS
Janse de Jonge 2012 V˙ O2max 40.0 ±6.9 mL/kg/min Recreationally active. Elevated in ML (37.2 ±0.3) vs. EF (37.0 ±0.2; P<0.05) NS NS Rest to 45-min was 19% higher in ML (P<0.05) 60-min fixed-intensity cycling (60% V˙ O2max), followed TTE TTE was 5.7% longer in EF than during ML (P<0.05)
Tenaglia 1999 V˙ O2max 44.8 ±2.6 mL/kg/min. Recreationally active. Elevated in ML (37.31 ±0.08) vs. EF (37.09 ±0.08; P<0.05) Elevated in ML (33.4 ±0.16) vs. EF (32.91 ±0.20; P<0.05) NS Elevated in EF vs. ML (P<0.05) 15-min walking, followed by 15-min seated rest until exhaustion TTE was longer in EF (128.1 ±13.4 min) vs. ML (107.4 ±8.6 min; P<0.05)

Abbreviations: L, luteal; F, follicular; EF, early follicular; ML, mid luteal; Tcore, core body temperature; Tsk, skin temperature; V˙ O2max, maximal oxygen consumption; TTE, time to exhaustion; TT, time trial; NS, no significant difference between the menstrual cycle phases (P>0.05); mean ±SD. Delta Tcore, difference between final and basal Tcore. * indicates the study used a mixed cohort of naturally menstruating and OCP users.