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TFII-I KO transiently increases Ad5-WT viral DNA replication. Parental and TFII-I KO BECs were infected with Ad5-WT at an MOI of 1, and total DNA was isolated at the indicated time post-infection. HAdV genome levels were quantified by qPCR and normalized to endogenous GAPDH levels. The results shown represent the mean values ± SD; n = 6. * =P ≤ 0.05, ** =P ≤ 0.01.
