Fig. 2.

Preparation and characterization of si-Cx43-NPs@Avastin-hydrogel (A) Schematic illustration of hydrogel synthesis (Avastin-hydrogel and si-Cx43-NPs@Avastin-hydrogel). (B) Images showing hydrogel gelation at room temperature and 37 °C. (C) Evaluation of hydrogel injectability. (D) SEM images of hydrogel surface morphology. (E) Rheological analysis measuring storage modulus (G′) and loss modulus (G″) of hydrogels across a temperature gradient. (F) Degradation properties of hydrogels in artificial tear fluid and citrate buffer (pH 5.5). (G) CAM assay evaluating anti-angiogenic activity of si-Cx43-NPs, single Avastin, and hydrogels.