Table 2. Investigation of the catalyst loading effect on the synthesis of compound 3aa.
| Entry | Amount of the catalyst system | Yieldb (%) |
|---|---|---|
| 1 | FeCl3·6H2O (5 mol%) | 78 |
| 2 | FeCl 3 ·6H 2 O (10 mol%) | 84 |
| 3 | FeCl3·6H2O (15 mol%) | 84 |
Reaction conditions: methyl arene 1a (1.0 mmol), acetophenone 2a (1.0 mmol), and iron as the catalyst 3a (10 mmol).
Isolated yields.