Table 3. Key downregulated proteins identified in G1 compared with G2.
| Accession number | Protein name | Gene | Score | Fold Change | Log(e) | SD | p | ED |
|---|---|---|---|---|---|---|---|---|
| P02808 | Statherin | STATH | 1181 | 5.15 | -1.64 | 0.09 | < 0.01 | ↓ |
| P23280 | Carbonic anhydrase 6 | CA6 | 580 | 5.00 | -1.61 | 0.05 | < 0.01 | ↓ |
| P05109 | Protein S100-A8 | S100A8 | 554 | 4.52 | -1.51 | 0.03 | < 0.01 | ↓ |
| Q9UGM3 | Deleted in malignant brain tumors 1 protein | DMBT1 | 31 | 3.15 | -1.15 | 0.05 | < 0.01 | ↓ |
| P07737 | Profilin-1 | PFN1 | 491 | 2.94 | -1.08 | 0.17 | < 0.01 | ↓ |
| P02814 | Submaxillary gland androgen-regulated protein 3B | SMR3B | 7816 | 2.69 | -0.99 | 0.01 | < 0.01 | ↓ |
| Q96DA0 | Zymogen granule protein 16 homolog B | ZG16B | 3747 | 2.05 | -0.72 | 0.03 | < 0.01 | ↓ |
| P04406 | Glyceraldehyde-3-phosphate dehydrogenase | GAPDH | 472 | 2.03 | -0.71 | 0.07 | < 0.01 | ↓ |
| Q5VSP4 | Putative lipocalin 1-like protein 1 | LCN1P1 | 79 | 2.01 | -0.7 | 0.06 | < 0.01 | ↓ |
| P02810 | Salivary acidic proline-rich phosphoprotein 1/2 | PRH1; PRH2 | 3562 | 1.97 | -0.68 | 0.03 | < 0.01 | ↓ |
| P59666 | Neutrophil defensin 3 | DEFA3 | 514 | 1.82 | -0.6 | 0.1 | 0.03 | ↓ |
| P06870 | Kallikrein-1 | KLK1 | 121 | 1.80 | -0.59 | 0.09 | < 0.01 | ↓ |
| P06744 | Glucose-6-phosphate isomerase | GPI | 43 | 1.75 | -0.56 | 0.11 | < 0.01 | ↓ |
| P31025 | Lipocalin-1 | LCN1 | 170 | 1.69 | -0.53 | 0.06 | < 0.01 | ↓ |
| P13929 | Beta-enolase | ENO3 | 44 | 1.63 | -0.49 | 0.18 | < 0.01 | ↓ |
| P62937 | Peptidyl-prolyl cis-trans isomerase A | PPIA | 124 | 1.63 | -0.49 | 0.16 | < 0.01 | ↓ |
| P54108 | Cysteine-rich secretory protein 3 | CRISP3 | 211 | 1.44 | -0.37 | 0.12 | 0.02 | ↓ |
| P01009 | Alpha-1-antitrypsin | SERPINA1 | 92 | 1.33 | -0.29 | 0.09 | < 0.01 | ↓ |
| P02647 | Apolipoprotein A-I | APOA1 | 81 | 1.27 | -0.24 | 0.08 | 0.01 | ↓ |
| P01036 | Cystatin-S | CST4 | 5005 | 1.20 | -0.19 | 0.02 | < 0.01 | ↓ |
| P22079 | Lactoperoxidase | LPO | 67 | 1.18 | -0.17 | 0.1 | 0.04 | ↓ |
| B9A064 | Immunoglobulin lambda-like polypeptide 5 | IGLL5 | 1340 | 1.12 | -0.12 | 0.06 | 0.04 | ↓ |
| P61626 | Lysozyme C | LYZ | 1239 | 1.12 | -0.12 | 0.07 | 0.04 | ↓ |
| P0DOX8 | Immunoglobulin lambda-1 light chain | IGL1 | 1340 | 1.12 | -0.12 | 0.05 | 0.01 | ↓ |
| P02768 | Albumin | ALB | 2966 | 1.11 | -0.11 | 0.02 | < 0.01 | ↓ |
| P09228 | Cystatin-SA | CST2 | 1072 | 1.08 | -0.08 | 0.02 | < 0.01 | ↓ |
| P12273 | Prolactin-inducible protein | PIP | 4781 | 1.06 | -0.06 | 0.03 | 0.01 | ↓ |
Note: Log (e) (“e” is a constant = 2.71); SD, standard deviation; p, statistical significance (adjusted by False Discovery Rate - FDR = 4); ED, Expression differences; ↓ = downregulated in G1 (p < 0.05). Bold lines indicate fold change higher than 2