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. 2025 Jun 3;10(23):24030–24049. doi: 10.1021/acsomega.4c08181

2. RMSD Comparisons between Different Modeling Approaches and Experimental Structures, Showing Both Unpruned and Pruned (in Parentheses) Values in Ångstroms.

PDB ID hybrid with AF templates RMSD hybrid with human AF RMSD AF3 vs Exp. RMSD AF2 vs Exp. RMSD
6D9H 2.594 (0.879) 2.615 (0.871) 2.630 (0.938) 2.594 (0.879)
7AUE 1.715 (1.126) 1.760 (1.028) 2.606 (1.095) 1.760 (1.028)
7F4D 1.698 (1.121) 1.403 (0.922) 1.841 (1.034) 1.403 (0.922)
7F53 1.145 (0.949) 1.767 (0.919) 1.741 (0.777) 1.766 (0.914)
7LD3 2.374 (0.857) 2.490 (0.905) 2.554 (0.992) 2.491 (0.914)
7PIU 2.357 (0.960) 1.538 (0.929) 2.263 (0.804) 1.537 (0.903)
7WKD 1.959 (1.008) 1.961 (0.990) 1.928 (1.017) 3.359 (0.930)
7X1T 2.078 (1.061) 2.080 (1.060) 2.057 (1.021) 2.081 (1.057)
8EFB 1.539 (0.807) 1.520 (0.813) 3.173 (1.018) 1.526 (1.067)
8F7Q 1.554 (0.860) 1.588 (0.864) 3.096 (1.107) 1.560 (1.035)
8F7W 2.715 (1.105) 2.725 (1.118) 3.168 (1.109) 2.727 (0.858)
8F7X 1.835 (0.954) 3.010 (1.032) 3.205 (1.008) 3.010 (1.118)
8HDO 3.428 (1.016) 3.333 (1.006) 3.279 (0.959) 3.340 (1.033)
8HTI 1.903 (1.022) 1.905 (1.048) 2.159 (0.874) 2.008 (0.998)
8ZPS 2.454 (1.053) 2.492 (1.059) 2.565 (1.107) 2.492 (1.071)