Table 3.
Comparison of ultrasound characteristics between bMF-ICC and pMF-ICC
| Ultrasound characteristics | Total (n = 141) | bMF-ICC (n = 33) | pMF-ICC (n = 108) |
Statistic | p-value |
|---|---|---|---|---|---|
| Tumor location (%) | χ2 = 4.90 | 0.03* | |||
| Left lobe | 65 (46.1%) | 21 (63.6%) | 45 (41.7%) | ||
| Right lobe | 76 (53.9%) | 12 (36.4%) | 63 (58.3%) | ||
| Grayscale ultrasound | |||||
| Echogenicity (%) | χ2 = 3.67 | 0.16 | |||
| Hyper-echogenicity | 14 (9.9%) | 4 (12.1%) | 10 (9.3%) | ||
| Iso-echogenicity | 11 (7.8%) | 5 (15.2%) | 6 (5.6%) | ||
| Hypo-echogenicity | 116 (82.3%) | 24 (72.7%) | 92 (85.2%) | ||
| Shape (%) | χ2 = 1.22 | 0.27 | |||
| Regular | 36 (25.5%) | 6 (18.2%) | 30 (27.8%) | ||
| Irregular | 105 (74.5%) | 27 (81.8%) | 78 (72.2%) | ||
| Margin (%) | χ2 = 1.08 | 0.30 | |||
| Clear | 58 (41.1%) | 11 (33.3%) | 47 (43.5%) | ||
| Ill-defined | 83 (58.9%) | 22 (66.7%) | 61 (56.5%) | ||
| CEUS | |||||
| The initial enhancement time (s) (IQR) | 17.00 (13.00–21.00) | 20.00 (14.50–21.00) | 17.00 (13.00–20.75) | z = −1.727 | 0.08 |
| Time to peak (s) (IQR) | 25.00 (20.00–30.00) | 27.00 (22.00–32.00) | 24.00 (20.00–28.00) | z = −1.715 | 0.09 |
| The washout time (s) (IQR) | 39.00 (32.00–50.00) | 42.00 (31.50–54.50) | 38.00 (32.00–49.50) | z = −1.267 | 0.21 |
| Contrast enhancement pattern (%) | χ2 = 0.30 | 0.86 | |||
| Circular enhancement | 67 (47.5%) | 17 (51.5%) | 50 (46.3%) | ||
| Non-circular enhancement | 52 (36.9%) | 11 (33.3%) | 41 (38.0%) | ||
| Nodular enhancement | 22 (15.6%) | 5 (15.2%) | 17 (15.7%) | ||
| Arterial phase enhancement degree (%) | χ2 = 0.32 | 0.85 | |||
| Hyper-enhancement | 132 (93.6%) | 31 (93.9%) | 101 (93.5%) | ||
| Iso-enhancement | 6 (4.3%) | 1 (3.0%) | 5 (4.6%) | ||
| Hypo-enhancement | 3 (2.1%) | 1 (3.0%) | 2 (1.9%) | ||
| Portal venous phase enhancement degree (%) | χ2 = 0.34 | 0.86 | |||
| Hyper-enhancement | 0 | 0 | 0 | ||
| Iso-enhancement | 5 (3.5%) | 1 (3.0%) | 4 (3.7%) | ||
| Hypo-enhancement | 136 (96.5%) | 32 (97.0%) | 104 (96.3%) | ||
| Late-phase enhancement degree (%) | χ2 = 0.80 | 0.37 | |||
| Hyper-enhancement | 0 | 0 | 0 | ||
| Iso-enhancement | 2 (1.4%) | 1 (3.0%) | 4 (3.7%) | ||
| Hypo-enhancement | 139 (98.6%) | 32 (97.0%) | 104 (96.3%) | ||
| Degree of clearance | χ2 = 0.18 | 0.67 | |||
| No clearance | 0 | 0 | 0 | ||
| Slight clearance | 130 (93.6%) | 31 (93.9%) | 99 (91.7%) | ||
| Significant clearance | 11 (7.8%) | 2 (6.1%) | 9 (8.3%) | ||
* p-value < 0.05