Table 1.

Molecular docking binding energies of designed compounds (9a-o).

Compound	Ar	Docking Scores (Kcal/Mol)
9a	Ph	−9.2
9b	2-ClC6H4	−8.9
9c	3-ClC6H4	−9.0
9d	4-ClC6H4	−8.9
9e	2-F-3-H3C–C6H3	−9.0
9f	2-H3CC6H4	−8.8
9g	2-H3CO–C6H4	−8.6
9h	4-H3CO–C6H4	−8.7
9i	2-F-3-Br-C6H3	−9.0
9j	4-FC6H4	−9.4
9k	2-F3C–C6H4	−9.0
9l	4-F3C–C6H4	−9.1
9m	3.4-diMeC6H3	−9.1
9n	4-BrC6H4	−9.3
9o	3-F3C-4-Br-C6H3	−9.2
Co-Crystal	PRU	−7.7
Acarbose		−7.8