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Anti α-glucosidase inhibitory activity of hybrids 9a-o.
| Compound | Ar | IC50 (nmol) |
|---|---|---|
| 9a | Ph | 15.17 |
| 9b | 2-ClC6H4 | 30.16 |
| 9c | 3-ClC6H4 | 23.22 |
| 9d | 4-ClC6H4 | 30.82 |
| 9e | 2-F-3-H3C–C6H3 | 30.16 |
| 9f | 2- H3CC6H4 | 21.74 |
| 9g | 2-H3CO–C6H4 | 18.68 |
| 9h | 4-H3CO–C6H4 | 38.71 |
| 9i | 2-F-3-Br-C6H3 | 16.19 |
| 9j | 4-FC6H4 | 14.69 |
| 9k | 2-F3C–C6H4 | 16.28 |
| 9l | 4-F3C–C6H4 | 28.71 |
| 9m | 3.4-diMeC6H3 | 16.19 |
| 9n | 4-BrC6H4 | 14.69 |
| 9o | 3-F3C-4-Br-C6H3 | 16.28 |
| Acarbose | 35.91 |
