Table 3.

Predicted Drug-Drug Interactions with Resmetirom and Mavorixafor.

New Approved Drugs	DrugBank ID1	Interacting Drugs	DrugBank ID2	Score	Interaction Description
Resmetirom	DB12914	Atorvastatin	DB01076	0.975	The serum concentration of Atorvastatin can be increased.
		Rosuvastatin	DB01098	0.601	The serum concentration of Rosuvastatin can be increased.
		Pitavastatin	DB08860	0.954	The serum concentration of Pitavastatin can be increased.
		Nefazodone	DB01149	0.948	The serum concentration of Resmetirom can be increased.
		Lovastatin	DB00227	0.981	The serum concentration of Lovastatin can be increased.
Mavorixafor	DB05501	Mirtazapine	DB00370	0.868	The risk or severity of QTc prolongation can be increased.
		Fluvastatin	DB01095	0.876	The metabolism of Fluvastatin can be decreased.
		Paliperidone	DB01267	0.838	The excretion of Mavorixafor can be decreased.
		Asenapine	DB06216	0.897	The risk or severity of QTc prolongation can be increased.
		Desvenlafaxine	DB06700	0.908	The metabolism of Mavorixafor can be decreased.