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. 2024 Dec 9;47(3):5069–5088. doi: 10.1007/s11357-024-01462-z

Table 2.

List of upregulated and downregulated proteins in the CF group with FC ≥  ± 2 and p < 0.05 when compared to the robust group

Gene Uniprot ID Protein name FC p-value
IGKV2-30 P06310 Immunoglobulin kappa variable 2–30 8.7 1.48E-04
IGLC2 P0DOY2 Immunoglobulin lambda constant 2 3.0 8.64E-08
IGHG4 P01861 Immunoglobulin heavy constant gamma 4 2.9 2.58E-03
IGHV5-10–1 A0A0J9YXX1 Immunoglobulin heavy variable 5–10-1 2.6 5.95E-04
IGLV2-11 P01706 Immunoglobulin lambda variable 2–11 2.5 1.26E-04
TTR P02766 Transthyretin 2.4 4.58E-10
GPX3 P22352 Glutathione peroxidase 3 2.4 2.05E-11
IGHV5-51 A0A0C4DH38 Immunoglobulin heavy variable 5–51 2.3 1.12E-04
SERPINC1 P01008 Antithrombin-III 2.2 9.00E-11
KRT10 P13645 Keratin, type I cytoskeletal 10 2.1 9.88E-04
HPR P00739 Haptoglobin-related protein 2.1 1.96E-07
ITIH4 Q14624 Inter-alpha-trypsin inhibitor heavy chain H4 2.1 2.97E-08
RBP4 P02753 Retinol-binding protein 4 2.0 1.18E-08
APOA2 P02652 Apolipoprotein A-II  − 2.0 3.16E-09
APOC2 P02655 Apolipoprotein C-II  − 2.1 8.45E-06
HBB P68871 Haemoglobin subunit beta  − 2.2 7.41E-04
APOE P02649 Apolipoprotein E  − 2.9 5.47E-12
APOA4 P06727 Apolipoprotein A-IV  − 3.0 2.19E-09
EEF1DP3 Q658K8 Putative elongation factor 1-delta-like protein  − 3.6 5.03E-06
APOC1 P02654 Apolipoprotein C-I  − 4.0 3.32E-10
APOA1 P02647 Apolipoprotein A-I  − 4.2 2.11E-10
DNAH1 Q9P2D7 Dynein axonemal heavy chain 1  − 5.3 1.20E-07

FC, fold change