Table 2.
List of upregulated and downregulated proteins in the CF group with FC ≥ ± 2 and p < 0.05 when compared to the robust group
| Gene | Uniprot ID | Protein name | FC | p-value |
|---|---|---|---|---|
| IGKV2-30 | P06310 | Immunoglobulin kappa variable 2–30 | 8.7 | 1.48E-04 |
| IGLC2 | P0DOY2 | Immunoglobulin lambda constant 2 | 3.0 | 8.64E-08 |
| IGHG4 | P01861 | Immunoglobulin heavy constant gamma 4 | 2.9 | 2.58E-03 |
| IGHV5-10–1 | A0A0J9YXX1 | Immunoglobulin heavy variable 5–10-1 | 2.6 | 5.95E-04 |
| IGLV2-11 | P01706 | Immunoglobulin lambda variable 2–11 | 2.5 | 1.26E-04 |
| TTR | P02766 | Transthyretin | 2.4 | 4.58E-10 |
| GPX3 | P22352 | Glutathione peroxidase 3 | 2.4 | 2.05E-11 |
| IGHV5-51 | A0A0C4DH38 | Immunoglobulin heavy variable 5–51 | 2.3 | 1.12E-04 |
| SERPINC1 | P01008 | Antithrombin-III | 2.2 | 9.00E-11 |
| KRT10 | P13645 | Keratin, type I cytoskeletal 10 | 2.1 | 9.88E-04 |
| HPR | P00739 | Haptoglobin-related protein | 2.1 | 1.96E-07 |
| ITIH4 | Q14624 | Inter-alpha-trypsin inhibitor heavy chain H4 | 2.1 | 2.97E-08 |
| RBP4 | P02753 | Retinol-binding protein 4 | 2.0 | 1.18E-08 |
| APOA2 | P02652 | Apolipoprotein A-II | − 2.0 | 3.16E-09 |
| APOC2 | P02655 | Apolipoprotein C-II | − 2.1 | 8.45E-06 |
| HBB | P68871 | Haemoglobin subunit beta | − 2.2 | 7.41E-04 |
| APOE | P02649 | Apolipoprotein E | − 2.9 | 5.47E-12 |
| APOA4 | P06727 | Apolipoprotein A-IV | − 3.0 | 2.19E-09 |
| EEF1DP3 | Q658K8 | Putative elongation factor 1-delta-like protein | − 3.6 | 5.03E-06 |
| APOC1 | P02654 | Apolipoprotein C-I | − 4.0 | 3.32E-10 |
| APOA1 | P02647 | Apolipoprotein A-I | − 4.2 | 2.11E-10 |
| DNAH1 | Q9P2D7 | Dynein axonemal heavy chain 1 | − 5.3 | 1.20E-07 |
FC, fold change