Table 2.
Univariate associations between one-year multidimensional outcomes and one-year health-related quality of life in 183 SAH patients
| MCS < 40 | MCS ≥ 40 | p-value | PCS < 40 | PCS ≥ 40 | p-value | MCS or PCS < 40 | MCS or PCS ≥ 40 | p-value | |
|---|---|---|---|---|---|---|---|---|---|
| Mental health impairments | |||||||||
| HADS-A > 7 | 38 (79) | 23 (17) | < 0.001 | 18 (51) | 43 (30) | 0.017 | 43 (65) | 18 (16) | < 0.001 |
| HADS-D > 7 | 24 (50) | 7 (5) | < 0.001 | 12 (34) | 19 (13) | 0.005 | 27 (41) | 4 (4) | < 0.001 |
| HADS-A > 10 | 17 (35) | 7 (5) | < 0.001 | 6 (17) | 18 (12) | 0.418 | 19 (30) | 5 (4) | < 0.001 |
| HADS-D > 10 | 10 (21) | 1 (0.8) | < 0.001 | 5 (14) | 6 (4) | 0.039 | 11 (17) | 0 (0) | < 0.001 |
| HADS-A | 9 (8–12) | 4 (2–6) | < 0.001 | 8 (4–10) | 5 (2–8) | 0.019 | 8 (6–11) | 4 (2–6) | < 0.001 |
| HADS-D | 8 (6–9) | 2 (1–4) | < 0.001 | 6 (2–10) | 3 (1–6) | < 0.001 | 6 (4–9) | 2 (0–4) | < 0.001 |
| FEDA-1 < 10th percentile | 25 (52) | 12 (9) | < 0.001 | 15 (43) | 22 (15) | 0.001 | 28 (42) | 9 (8) | < 0.001 |
| FEDA-2 < 10th percentile | 40 (83) | 32 (24) | < 0.001 | 33 (94) | 39 (26) | < 0.001 | 56 (85) | 16 (14) | < 0.001 |
| FEDA-3 < 10th percentile | 20 (43) | 3 (2) | < 0.001 | 13 (37) | 10 (7) | < 0.001 | 22 (34) | 1 (1) | < 0.001 |
| Cognitive deficits | |||||||||
| Any domain | 36 (78) | 69 (58) | 0.019 | 26 (84) | 79 (59) | 0.012 | 49 (79) | 56 (54) | 0.002 |
| Executive deficits | 17 (36) | 22 (18) | 0.024 | 14 (44) | 25 (18) | 0.004 | 23 (37) | 16 (15) | 0.002 |
| Visuoconstructive deficits | 15 (32) | 34 (25) | 0.446 | 10 (29) | 39 (27) | 0.831 | 21 (32) | 28 (24) | 0.295 |
| Memory deficits | 29 (63) | 51 (39) | 0.006 | 19 (58) | 61 (43) | 0.127 | 39 (61) | 41 (37) | 0.003 |
| Attention deficits | 6 (13) | 18 (13) | 1.000 | 6 (18) | 18 (12) | 0.404 | 7 (11) | 17 (15) | 0.648 |
| Functional outcomes | |||||||||
| mRS at 12 months | 1 (1–2) | 0 (0–1) | < 0.001 | 1 (1–2) | 0 (0–1) | < 0.001 | 1 (1–2) | 0 (0–1) | < 0.001 |
Mental component summary, PCS Physical component summary, HADS Hospital anxiety and Depression scale, mRS Modified Rankin scale score, FEDA Fragebogen Erlebter Defizite der Aufmerksamkeit, FEDA-1 Distractibility, FEDA-2 Tiredness, fatigue, FEDA-3 Reduction in drive
Data are given in n (%) or median (IQR). Univariate analysis was done with the Fisher’s exact test or Mann–Whitney U test, as appropriate
Bold numbers signify statistical differences p<0.05