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. 2025 Jun 19;18:3239–3251. doi: 10.2147/IJGM.S521565

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© 2025 Wang et al.

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The validation of hub genes. (A) ROC curve of hub genes in UC diagnosis. (B) Box plots show differences between UC and control for each of the hub genes using merged GEO datasets. (C) Box plots show differences between UC and control for each of the hub genes using GSE87473 dataset. (D and E) Representative PPARGC1A and SLC6A4 staining (scale bar represents 50 μm) and analysis of colon tissues. (F and G) PPARGC1A and SLC6A4 protein levels in normal and UC groups by Western blotting. The data were presented as the mean ± SEM, with significance indicated by **p<0.01, ***p<0.001.