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. Author manuscript; available in PMC: 2025 Jul 1.
Published in final edited form as: Physiol Rev. 2025 Jan 15;105(3):1033–1074. doi: 10.1152/physrev.00012.2024

Figure 8.

Figure 8.

Physiological function of TRPM4 in cardiomyocytes. Solid red arrows indicate calcium flow; dash red arrows indicate calcium regulation targets. Solid black, deep blue, and orange arrows indicate sodium, potassium, and chloride flow, respectively. Only selected ion channels are highlighted in this illustration. PMCA, plasma membrane Ca2+ ATPase; NCX, sodium-calcium exchanger; CaCCs, calcium-activated chloride channels; SERCA, sarcoendoplasmic reticulum calcium ATPase; SR, sarcoplasmic reticulum; Nav, voltage-gated sodium channel subtype 1.5; Cav, voltage-gated calcium channel subtype 1.2; K channels represent a collection of potassium-selective channels.