Table 2.
TRPM4 expression in mammalian species
| Organ/Tissue | Species | References | Methods |
|---|---|---|---|
| Cardiovascular system | |||
| heart | human | Launay, 2002, Fonfria, 2006; Kruse, 2009; Dragun, 2019; Frede, 2020; Feng, 2021 | RT-PCR, qPCR, Northern blot, WB, ICC, IHC, IF, patch clamp |
| rat | Guinamard, 2006; Teruyama, 2011; Piao, 2015; Son, 2016; Frede, 2020 | ||
| mouse | Demion, 2007; Jang, 2012; Simard, 2012; Kecskés, 2015; Gueffier, 2017; Medert, 2020; Frede, 2020; Guo, 2021; Hedon, 2021; Medert, 2021; Arullampalam, 2023 | ||
| dog | Dienes, 2021 | ||
| rabbit | Hof, 2016 | ||
| blood vessel | human | Thilo, 2011; Echeverría, 2015 | |
| rat | Earley, 2004; Yang, 2006; Gerzanich, 2009; Crnich, 2010; Li, 2014; Ding, 2017; Gong, 2019; Csipo, 2022 | ||
| mouse | Ali, 2021; Yamasaki, 2023 | ||
| Immune system | |||
| bone marrow | human | Fonfria, 2006 | qPCR, Northern blot, IHC, IP, WB, patch clamp |
| spleen | Launay, 2002; Fonfria, 2006 | ||
| thymus | Launay, 2002; Launay, 2004 | ||
| blood mononuclear cell | Fonfria, 2006; Serafini, 2012; Malhotra, 2013; Morita, 2020; Wang, 2020; Çakir, 2021; Ozcan, 2021 | ||
| macrophage | Fonfria, 2006 | ||
| T cell | mouse | Launay, 2004; Vennekens, 2007; Weber, 2010 | |
| mast cell | Vennekens, 2007 | ||
| macrophage | Serafini, 2012 | ||
| dendritic cell | Barbet, 2008 | ||
| Nervous system | |||
| cerebrum | human | Fonfria, 2006; Schattling, 2012; Tosun, 2013; Mehta, 2015; Hristov, 2016 | RT-PCR, qPCR, WB, ICC, IHC, IF, IP, in situ hybridization, FRET, patch clamp |
| rat | Li, 2010; Teruyama, 2011; Tosun, 2013; Huang, 2015; Huang, 2016; Chen, 2019; Ma, 2023 | ||
| mouse | Crowder, 2007; Jang, 2012; Schattling, 2012; Riquelme, 2018; Yan, 2020; Riquelme, 2021 | ||
| cerebellum | mouse | Kim, 2013 | |
| brainstem | rat | Koizumi, 2018 | |
| mouse | Koizumi, 2018; Li, 2021 | ||
| pituitary | human | Fonfria, 2006 | |
| spinal cord | human | Schattling, 2012 | |
| rat | Woo, 2013; Turtle, 2019 | ||
| mouse | Schattling, 2012; Vandewauw, 2013; Bianchi, 2018; Yao, 2018; Tsymbalyuk, 2021 | ||
| Urogenital system | |||
| bladder | human | Hristov, 2016 | RT-PCR, qPCR, Northern blot, WB, ICC, IHC, IF, patch clamp |
| rat | Smith, 2013a | ||
| mouse | Yu, 2011; Kullmann, 2018 | ||
| guinea pig | Smith, 2013b; Maxwell, 2021 | ||
| kidney | human | Launay, 2002; Fonfria, 2006 | |
| rat | Teruyama, 2011; Dusmez, 2014; Piao, 2015 | ||
| mouse | Jang, 2012 | ||
| placenta | human | Launay, 2002; Fonfria, 2006 | |
| uterus | human | Fonfria, 2006; De Clercq, 2015; Persoons, 2018 | |
| mouse | De Clercq, 2017 | ||
| prostate | human | Fonfria, 2006; Hristov, 2016 | |
| rat | Wang, 2007 | ||
| testis | rat | Li, 2010; Jang, 2012 | |
| Respiratory system | |||
| lung | human | Fonfria, 2006 | RT-PCR, qPCR, IHC |
| rat | Piao, 2015 | ||
| mouse | Jang, 2012 | ||
| Digestive system | |||
| liver | human | Launay, 2002; Fonfria, 2006 | RT-PCR, qPCR, Northern blot |
| rat | Piao, 2015 | ||
| stomach | human | Fonfria, 2006 | |
| intestine | human | Fonfria, 2006 | |
| Sensory system | |||
| inner ear | mouse | Takumida, 2009; Sukuraba, 2014 | RT-PCR, qPCR, WB, IHC, IF, patch clamp |
| eye | human | Yarishkin, 2022 (trabecular meshwork cells) | |
| mouse | Choi, 2015 (optic nerve head) | ||
| tongue | rat | Teruyama, 2011 | |
| Others | |||
| pancreas | human | Launay, 2002; Fonfria, 2006; Marigo, 2009 | RT-PCR, qPCR, Northern blot, WB, IP, ICC, IHC, patch clamp |
| rat | Cheng, 2007; Marigo, 2009; Piao, 2015, Ma, 2017 | ||
| mouse | Marigo, 2009; Nelson, 2011; Diszházi, 2021 | ||
| hamster | Marigo, 2009 | ||
| skin | human | Fonfria, 2006; Vennekens, 2007; Wang 2019; Otsuka Saito, 2023 | RT-PCR, qPCR, Northern blot, WB, patch clamp |
| skeletal muscle | human | Launay, 2002 | |
| mouse | Krüger, 2008 | ||
| breast | human | Wong, 2020 | |
| stem cell | human | Tran, 2014 | |
| rat | Nelson, 2013 | ||
| adipose | human | Fonfria, 2006; Tran, 2014 | |