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. Author manuscript; available in PMC: 2025 Jul 1.
Published in final edited form as: Physiol Rev. 2025 Jan 15;105(3):1033–1074. doi: 10.1152/physrev.00012.2024

Table 3.

TRPM5 expression in mammal species

Organ/Tissue Species References Methods
Taste tissue
tongue monkey Gonda, 2013 RT-PCR, qPCR, Northern blot, in situ hybridization, IF, WB, TRPM5-GFP mice, patch clamp
rat Teruyama, 2011; Padalhin, 2022
mouse Pérez, 2002; Pérez, 2003; Zhang, 2003; Clapp, 2006; Kaske, 2007; Zhang, 2007; Liu, 2011; Herrera Moro Chao, 2016; Cui, 2019; Wu, 2020; Nguyen, 2021
chicken Yoshida, 2017
palate chicken Yoshida, 2017
Olfactory system
main olfactory epithelium mouse Kaske, 2007; Lin, 2007; Lin, 2008b; Nakashimo, 2010; Oshimoto, 2013; López, 2014; Yamaguchi, 2014; Fu, 2018; Genovese, 2018; Lemons, 2020; Dnate Baxter, 2021 in situ hybridization, IHC, IF, TRPM5-GFP mice, patch clamp
GI tract
oesophagus human Young, 2008 RT-PCR, qPCR, IHC, IF, Northern blot, in situ hybridization, WB, TRPM5-eGFP mice
stomach human Young, 2008; Widmayer, 2012
monkey Gonda, 2013
mouse Pérez, 2002, Pérez, 2003; Kaske, 2007; Cui, 2019
intestine human Fonfria, 2006; Young, 2008
monkey Gonda, 2013
rat Feng, 2017; Kang, 2020
mouse Pérez, 2002; Pérez, 2003; Kaske, 2007; Bezençon, 2008; Young, 2008; Kokrashvili, 2009; Herrera Moro Chao, 2016; Howitt, 2016; Cui, 2019; Zheng, 2023
Respiratory system
lung mouse Herrera Moro Chao, 2016 RT-PCR, qPCR, IHC, IF, TRPM5-GFP mice, patch clamp
trachea rat Kaske, 2007
mouse Kaske, 2007; Herrera Moro Chao, 2016; Genovese, 2018
bronchus mouse Kaske, 2007
nose human Barham, 2013
mouse Kaske, 2007; Lin, 2008a
Brain
third ventricle mouse Yu, 2023 RT-PCR, qPCR, ICC, IHC, IF, TRPM5-GFP mice
hippocampus mouse Herrera Moro Chao, 2016
cortex mouse Herrera Moro Chao, 2016
hypothalamus rat Teruyama, 2011
mouse Herrera Moro Chao, 2016
amygdala mouse Thompson, 2012
cerebellum mouse Kim, 2013
brainstem mouse Crowder, 2007; Herrera Moro Chao, 2016
pituitary human Fonfria, 2006
Others
pancreas human Fonfria, 2006 RT-PCR, qPCR, WB, IF, patch clamp
rat Prawitt, 2003
mouse Colsoul, 2010; Colsoul, 2014
heart rat Teruyama, 2011
kidney human Fonfria, 2006
rat Liu, 2011; Teruyama, 2011
mouse Crowder, 2007; Cui, 2019
prostate human Fonfria, 2006
skin human Mardaryev, 2021
odontoblast mouse Khatibi Shahidi, 2015