Table 3. Group means, SDs, and P values comparing timepoints with effect sizes of participants randomized to use the DCP^a versus a control.

Outcome	Group
	Baseline, mean (SD)	3 weeks, mean (SD)	P value (comparing baseline to 3 weeks)	6 weeks, mean (SD)	P value (comparing 3 weeks to 6 weeks)	Effect Size (Hedges g; baseline to 6 weeks)
Primary outcomes
HFRSb—Problem						0.64
Caria DCP (n=103)	16.4 (6.7)	14.7 (6.3)c	.001	13.6 (6.6)c	.005
Control (n=37)	19.1 (7.3)	16.9 (7.4)c	.002	17.8 (7.2)	.24
HFRS—Frequency						0.02
Caria    DCP (n=103)	2.8 (2.7)	2.5 (4.1)	.50	2.9 (5.4)	.61
Control (n=37)	2.3 (3.2)	2.2 (2.7)	.94	2.7 (2.7)	.30
Exploratory outcomes
Depression (PHQ-8)						0.45
Caria    DCP (n=50)d	14.0 (3.8)	12.2 (4.7)c	.002	11.2(5.3)c	.02
Control (n=21)	15.0 (3.7)	13.3 (4.5)	.12	13.4 (4.1)	.93
Sleep Disturbance (PSQI)						0.25
Caria    DCP (n=100)e	10.7 (3.1)	10.0 (3.4)c	<.001	10.0 (3.5)	.81
Control (n=35)f	11.5 (3.7)	10.9 (4.0)	.10	11.0 (3.7)	.82
Anxiety (GAD-7)						0.33
Caria    DCP (n=35)	14.8 (3.3)	13.3 (4.7)c	.02	12.7 (5.5)	.36
Control (n=15)g	16.0 (3.8)	12.9 (5.4)c	.02	14.5 (4.5)	.13

^aDCP: digital care program.

^bHFRS: Hot Flush Rating Scale.

^cP<.05

^dFor 3 and 6 weeks, n=49.

^eFor 3 and 6 weeks, n=97.

^fFor 3 and 6 weeks, n=32.

^gFor 3 and 6 weeks, n=14.