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. Author manuscript; available in PMC: 2025 Jun 25.
Published in final edited form as: Sex Transm Dis. 2025 Mar 4;52(5):295–303. doi: 10.1097/OLQ.0000000000002089

TABLE 3.

Syphilis Screening for 18- to 49-Year-Old Pregnant Women in Commercial Insurance Claims Data With State Laws During the Third Trimester and Any Time According to Age, Centers for Medicare & Medicaid Service Region, Employee Classification, and Type of Health Care Insurance, 2022 MarketScan Data

3rd Trimester Any Screening During Pregnancy
Total No. Pregnant Women Residing in State With Screening Law* No. Screened According to Law Odds Ratio (95% CI) No. Pregnant Women Residing in State With Screening Law§ No. Screened According to law
N (Col %) N (%) n (%) N (Row %) n (Row%) Odds Ratio (95% CI)
Total 170,005 (100) 95,077 (55.93) 69,063 (72.64) 1.02 (0.99–1.04) 144,731 (95.06) 116,101 (80.2) 1.1 (1.1–1.2)
Age category, y
 18–24 19,684 (11.58) 11,517 (64.50) 8,108 (70.40) 0.82 (0.67–0.99) 17,032 (95.39) 13,182 (77.40) 0.81 (0.65–1.00)
 25–34 106,496 (62.64) 58,886 (62.25) 42,864 (72.79) 0.90 (0.74–1.09) 89,718 (94.84) 72,365 (80.66) 0.98 (0.79–1.21)
 35–44 43,211 (25.42) 24,337 (62.01) 17,838 (73.30) 0.93 (0.76–1.13) 37,450 (95.42) 30,126 (80.44) 0.96 (0.78–1.19)
 45–49 614 (0.36) 337 (60.72) 253 (75.07) Reference 531 (95.68) 428 (80.60) Reference
Centers for Medicare & Medicaid Services regions**
 1 (Connecticut, Maine, Massachusetts, 7,545 (4.44) New Hampshire, Rhode Island, Vermont) 2,553 (33.84) 1,912 (74.89) 1.19 (1.12–1.26) 6,623 (87.78) 5,464 (82.50) 1.26 (1.19–1.35)
 2 (New Jersey, New York) 11,936 (7.03) 0 (0.00) 0 (0.00) 0.95 (0.90–1.00) 11,927 (99.92) 9,547 (80.05) 1.09 (1.03–1.14)
 3 (Delaware, District of Columbia, Maryland, Pennsylvania, Virginia, West Virginia) 16,048 (9.45) 9,145 (56.99) 6,560 (71.73) 1.16 (1.11–1.21) 16,048 (100.00) 13,148 (81.93) 1.23 (1.17–1.28)
 4 (Alabama, Florida, Georgia, Kentucky, Mississippi, North Carolina, South Carolina, Tennessee) 51,112 (30.10) 34,275 (84.01) 24,074 (70.24) Reference 39,850 (97.67) 31,372 (78.73) Reference
 5 (Illinois, Indiana, Michigan, Minnesota, Ohio, Wisconsin) 26,858 (15.82) 9,055 (46.16) 6,658 (73.53) 0.97 (0.94–1.01) 15,559 (79.31) 12,447 (80.00) 1.06 (1.01–1.11)
 6 (Arkansas, Louisiana, New Mexico, Oklahoma, Texas) 18,767 (11.05) 18,534 (98.76) 15,051 (81.21) 1.80 (1.72–1.87) 18,767 (100.00) 16,088 (85.72) 1.63 (1.56–1.71)
 7 (Iowa, Kansas, Missouri, Nebraska) 7,480 (4.40) 3,659 (48.92) 2,811 (76.82) 1.24 (1.17–1.31) 6,102 (81.58) 5,016 (82.20) 1.36 (1.27–1.45)
 8 (Colorado, Montana, North Dakota, South Dakota, Utah, Wyoming) 4,637 (2.73) 0 (0.00) 0 (0.00) 0.73 (0.68–0.79) 4,444 (95.84) 3,395 (76.40) 0.85 (0.79–0.91)
 9 (Arizona, California, Hawaii, Nevada, Pacific Territories) 17,878 (10.53) 17,856 (99.88) 11,997 (67.19) 0.84 (0.81–0.88) 17,856 (99.88) 13,642 (76.40) 0.87 (0.84–0.91)
 10 (Alaska, Idaho, Oregon, Washington) 7,555 (4.45) 0 (0.00) 0 (0.00) 0.86 (0.81–0.926) 7,555 (100.00) 5,982 (79.18) 1.03 (0.97–1.10)
Employee classification††
 Hourly 40,218 (44.65) 24,130 (60.00) 17,481 (72.45) 0.96 (0.93–0.99) 36,088 (95.49) 28,880 (80.03) 0.89 (0.86–0.92)
 Salary 49,861 (55.35) 27,886 (55.93) 20,518 (73.58) Reference 41,338 (92.20) 33,830 (81.84) Reference
Type of health care insurance plan‡‡
 HMO 19,824 (12.17) 13,763 (81.23) 9,993 (72.61) 0.96 (0.92–0.99) 16,279 (96.08) 13,000 (79.86) 0.97 (0.93–1.02)
 PPO 78,720 (48.34) 40,683 (60.45) 29,725 (73.06) Reference 64,832 (96.34) 15,771 (80.32) Reference
 POS 20,468 (12.57) 11,155 (55.33) 8,101 (72.62) 1.05 (1.02–1.09) 19,634 (97.39) 52,054 (80.29) 1.00 (0.96–1.04)
 CDHP 18,110 (11.1287) 9,872 (59.64) 7,141 (72.34) 1.05 (1.01–1.09) 15,602 (94.25) 12,673 (81.23) 1.07 (1.02–1.11)
 HDHP 25,739 (15.80) 15,474 (62.73) 11,089 (71.66) 0.96 (0.93–0.99) 22,678 (91.93) 18,081 (79.73) 0.97 (0.93–1.00)
 Other 3,737 (2.24) 1,985 (59.61) 1,425 (71.79) 0.85 (0.79–0.92) 3,006 (90.27) 2,355 (78.34) 0.88 (0.81–1.04)
*

Number and percentage of women who resided in a state with a law requiring third-trimester screening.

Number and percentage of the pregnant women residing in a state with a law requiring third-trimester screening who were screened for syphilis.

Odds ratios were calculated with the reference categories (age: 45–49 years; CMS region: 10; salary, PPO) and regulation requiring syphilis screening during a specific gestation period.

§

Number and percentage of women who resided in a state with a law requiring syphilis screening anytime during pregnancy. N = 152,256; Missing = 17,749.

Number and percentage of the pregnant women residing in a state with a law requiring anytime during pregnancy screening who were screened for syphilis.

Odds ratios were calculated for the women residing in a state with laws versus the states without current laws on the specific screening time.

**

Centers for Medicare & Medicaid Services regions contain regional offices to ensure that health care providers are meeting federal requirements. Missing = 189.

††

Employment classification of the primary beneficiary (Salary Non-union, Salary Union, Salary Other combined for Salary; Hourly Non-union, Hourly Union, Hourly Other combined for Hourly; N = 90,079).

‡‡

Type of benefit plan, HMO, PPO, POS, CDHP, HDHP, Other; third-trimester law population: N = 92,932, Missing = 21,052; population: N = 148,953, Missing = 21,052.

Col% indicates column percent; Other, other basic or major medical comprehensive exclusive provider organizations; Row%, row percent.