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Schematic diagram of the study design. NLRP3: NLR family pyrin domain containing 3; IL: Interleukin; RT-qPCR: Reverse transcription and quantitative real-time PCR; IHC: Immunohistochemistry; IF: Immunofluorescence; ROS: Reactive oxygen species; CEL: Celastrol; PRED: Prednisolone; LPS: Lipopolysaccharide; ATP: Adenosine triphosphate; HE: Hematoxylin-eosin.
