Correction to: Hepatocellular carcinoma xenograft supports HCV replication: A mouse model for evaluating antivirals

Abstract

This is an erratum to the published paper titled “Hepatocellular carcinoma xenograft supports HCV replication: A mouse model for evaluating antivirals”. Figure 9 panels shown weeks 2 and weeks 4 were duplicated. This correction is requested to ensure the accuracy of the information provided in this article.

Core Tip: This correction is to: Hazari S, Hefler HJ, Chandra PK, Poat B, Gunduz F, Ooms T, Wu T, Balart LA, Dash S. Hepatocellular carcinoma xenograft supports HCV replication: a mouse model for evaluating antivirals. World J Gastroenterol 2011; 17 (3): 300-312, PMID: 21253388 DOI: 10.3748/wjg.v17.i3.300. The purpose of figure 9 in this article is to show that interferon treatment does not reduce tumor growth. The histology panel shown in weeks 2 and 4 were duplicated. As the corresponding author, I am submitting a corrected figure. This correction is requested to ensure the accuracy of the information provided in this article. This correction does not impact the conclusion of the manuscript.

CORRECTION

This is a correction to: Hazari S, Hefler HJ, Chandra PK, Poat B, Gunduz F, Ooms T, Wu T, Balart LA, Dash S. Hepatocellular carcinoma xenograft supports HCV replication: A mouse model for evaluating antivirals. World J Gastroenterol 2011; 17(3): 300-312 [PMID: 21253388 DOI: 10.3748/wjg.v17.i3.300].

This article[1] was published in 2011. It came to my attention that figure 9 panels shown weeks 2 and weeks 4 were duplicated. As the corresponding author, I am submitting a corrected figure (Figure 1). This correction is requested to ensure the accuracy of the information provided in this article. This correction does not impact the conclusion of the manuscript.

Figure 1.

Histological evaluation of liver sections after hematoxylin and eosin staining indicates that interferon-α treatment did not cause tumor necrosis or reduce the size of tumor nodules in the SCID mice liver. A: The upper panel shows the untreated mouse liver sections after 3 and 5 weeks of tumor development. The black arrows indicate the hepatocellular carcinoma (HCC) tumor in the mouse liver. Similarly, the lower panel shows the interferon-α-treated mouse liver sections with HCC tumor at different time points (10 × magnification); B: Interferon a treatment did not reduce the size of the HCC tumor in the mouse liver. An improved version of the histology images was prepared by enhancing contrast, brightness, and color balance. The upper panel shows the untreated mouse liver sections after 3 and 5 weeks of tumor development. The pseudo-color boundary indicates the HCC tumor in the mouse liver before interferon a treatment. Similarly, the lower panel shows the interferon-α-treated mouse liver sections with HCC tumor at different time points (10 × magnification).

ACKNOWLEDGEMENTS

We thank the reviewer for these constructive comments.