Table 3.

Reported outcomes per study

Author [ref.]	Time of outcome assessment in weeks	Pain intensity, mean difference (95% CI)	p value	Sleep interference, mean difference (95% CI)	p value
Markman et al. [21]	15	-0.22 (-0.54 to 0.10)	0.18	-0.43 (-0.71 to -0.14)	0.0031
van Seventer et al. [33]	8	-0.62 (-1.1 to -0.15)	0.010	-0.79 (-1.3 to -0.34)	0.001
Gordh et al. [10]a	5	-0.030 (-0.69 to 0.63)	0.93	-0.39 (-0.95 to 0.17)	0.17
Gordh et al. [10]b	5	-0.46 (-0.88 to -0.036)	0.036	-0.33 (-0.72 to 0.062)	0.10
Jenkins et al. [13]a	2	-0.47 (-1.3 to 0.31)	0.25
Jenkins et al. [13]b	2	-1.1 (-2.0 to -0.15)	0.034

A negative number means greater reduction in gabapentinoid than placebo group. Both pain intensity and sleep interference were measured on a scale from 0 to 10. The MCID was assumed to be -2 for pain intensity and -1.5 for sleep interference.

^aBefore unblinding.

^bAfter unblinding.