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. 2025 Jun 19;13(6):1504. doi: 10.3390/biomedicines13061504
Akt Protein kinase B
ALP Alkaline phosphatase
APC Adenomatous polyposis coli
AXIN Axis inhibition protein
BA/TA Bone area/total area
BFR Bone formation rate
BMAD Bone mineral apparent density
BMC Bone mineral content
BMD Bone mineral density
BMI Body mass index
BMP-2 Bone morphogenic protein-2
BMPRI BMP type I receptor
BMPRII BMP type II receptor
BSP Bone sialoprotein
BV/TV Bone volume/total volume
CI Confidence interval
CK1α Casein kinase alpha
COL1 Type I collagen
Conn.D Connectivity density
Co-Smad Common-mediator Smad
CTSK Cathepsin K
Ct.Ar Cortical area
Ct.Ar/Tt.Ar Cortical area fraction
Ct.Th Cortical thickness
CTX Carboxyl-terminal cross-linked telopeptide of type 1 collagen
DKK1 Dickkopf-related protein 1
dLS Double-labelled surface
Dlx5 Distal-less homeobox 5
DVL Protein dishevelled
ES Eroded surface
Foxo1 Forkhead box protein O1
GLUT4 Glucose transporter 4
GSK3β Glycogen synthase kinase 3-beta
HOMA-IR Homeostatic model assessment of insulin resistance
HOMA-β Homeostatic model assessment of β-cell function
HR Hazard ratio
IKK Inhibitor of nuclear factor-kappa B
IRS Insulin receptor substrate
IRβ Insulin receptor β
I-Smads Inhibitory Smads
KK-Ay Yellow Kuo Kondo
LEF Lymphoid enhancer-binding factor
LRP5 Low-density lipoprotein receptor-related protein 5
MAR Mineral apposition rate
METS-IR Metabolic score for insulin resistance
MS Mineralising surface
NF-κB Nuclear factor-kappa B
NHANES National Health and Nutrition Examination Survey
Ob.N Osteoblast number
Ob.S Osteoblast surface
Oc.N Osteoclast number
Oc.S Osteoclast surface
OCN Osteocalcin
OPG Osteoprotegerin
OR Odds ratio
OS Osteoid surface
OSX Osterix
OV Osteoid volume
PIP2 Phosphorylates phosphatidylinositol 4,5-bisphosphate
PIP3 Phosphatidylinositol 3,4,5-trisphosphate
PI3K Phosphatidylinositol 3-kinase
P1NP N-terminal propeptide of type 1 collagen
p-Akt Phosphorylated protein kinase B
p-β-catenin Phosphorylated β-catenin
p-GSK3β Phosphorylated glycogen synthase kinase 3-beta
QUICKI Quantitative insulin sensitivity check index
RANK Receptor activator of nuclear factor kappa B
RANKL Receptor activator of nuclear factor kappa-B ligand
R-Smads Receptor-regulated Smads
Runx2 Runt-related transcription factor 2
sFRP Secreted Frizzled-related proteins
sLS Single-labelled surface
Smad Suppressor of mothers against decapentaplegic
SMI Structure model index
Sost Sclerostin
STZ Streptozotocin
TAB2 TAK1 binding protein 2
TAB3 TAK1 binding protein 3
TAK1 Transforming growth factor beta-activated kinase 1
Tb.N Trabecular number
Tb.Sp Trabecular separation
Tb.Th Trabecular thickness
TCF T-cell-specific factor
TGF-β Transforming growth factor-beta
TRAF6 Tumour necrosis factor receptor-associated factor 6
TRAP Tartrate-resistant acid phosphatase
Tt.Ar Total cross-sectional area inside the periosteal envelope
TyG Triglyceride–glucose index
TyG-BMI Tyg index with body mass index
TyG-WC Tyg index with waist circumference
TyG-WHtR Tyg index with waist-to-height ratio
T1DM Type 1 diabetes mellitus
T2DM Type 2 diabetes mellitus
ucOCN Uncarboxylated osteocalcin
V-ATPase V-type proton atpase
Wnt3a Wnt ligand 3a
β-catenin Beta-catenin