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. 2025 Jun 3;11(6):430. doi: 10.3390/gels11060430
DM diabetes mellitus
DFU diabetic foot ulcer
VSMC vascular smooth muscle cell
AGEs advanced glycation end products
PARP poly-ADP ribose polymerase
COX-2 cyclooxygenase-2
ECM extracellular matrix
IL-1 interleukin- 1
IL-6 interleukin-6
TNF α tumor necrosis factor alpha
CRP C-reactive protein
VEGF vascular endothelial growth factor
Nrf2 nuclear factor erythroid-2-related factor 2
ROS reactive oxygen species
MMP 2 metalloproteinase 2
MMP 9 metalloproteinase 9
TGF β tumor growth factor beta
PDGF platelet-derived growth factor
HBOT hyperbaric oxygen therapy
NPWT negative pressure wound therapy
PRP platelet-rich plasma
ESCs embryonic stem cells
iPSCs induced pluripotent stem cells
MSCs mesenchymal stem cells
BM-MSCs bone-marrow-derived MSCs
ASCs adipose-derived MSCs
SVF stromal vascular fraction
T2DM type 2 diabetes mellitus
FGF-2 fibroblast growth factor-2
IGF-1 insulin growth factor-1
HGF hepatocyte growth factor
KGF keratinocyte growth factor
EXOs exosomes
DNA deoxyribonucleic acid
RNA ribonucleic acid
miRNA micro ribonucleic acid
IFN-α interferon alpha
MFAT micro-fragmented adipose tissue
GLP-1 glucagon-like peptide-1
HA hyaluronic acid
UHMWA-HA ultra-high molecular weight hyaluronic acid
pDA polydopamine
EGF epidermal growth factor
IL-10 interleukin 10