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Overexpression of MAP7 might inhibit tumor proliferation, migration, and the invasion of osteosarcoma cells. (A) Expression of MAP7 in hFOB1.19, HOS, U-2OS, and SAOS-2 cells. Overexpression efficiency of MAP7 was evaluated by qRT-PCR (B) and Western blotting (C). (D) Cell proliferation was detected using CCK-8 assays. (E) The ability of cell migration and invasion was detected using the Transwell assay. * means P < 0.05, **P < 0.01, *** means P < 0.001, and **** means P < 0.0001.
