Table 2. Baseline variables of the study population by age and gender groups.
| Variables | Youth group (18–34 years) | Middle-aged group (35–55 years) | Middle-aged and elderly group (≥56 years) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Female | Male | Female | Male | Female | Male | |||||||
| Cases (n = 228) | Controls (n = 100) | Cases (n = 116) | Controls (n = 86) | Cases (n = 696) | Controls (n = 319) | Cases (n = 232) | Controls (n = 191) | Cases (n = 290) | Controls (n = 109) | Cases (n = 88) | Controls (n = 77) | |
| Age (year) | 29.6 ± 3.5 | 29.9 ± 2.5 | 29.8 ± 3.0 | 30.3 ± 2.6 | 45.5 (39.3–51) | 44 (40–50) | 44.4 ± 6.5 | 44.5 ± 5.9 | 61.3 ± 5.1 | 62.2 ± 4.6 | 61.6 ± 5.1 | 60.5 ± 4.4 |
| BMI | 21.99 ± 3.19 | 20.37 ± 2.45** | 24.6 ± 3.65 | 23.34 ± 2.63* | 22.73 ± 3.02 | 21.87 ± 2.54** | 25.03 ± 3.03 | 24.26 ± 2.76* | 23.30 ± 3.01 | 22.94 ± 2.86 | 24.27 ± 2.97 | 24.10 ± 2.63 |
| FBG (mmol/L) | 4.80 (4.55–5.08) | 4.68 (4.44–4.97)* | 4.78 (4.52–5.09) | 4.78 (4.58–5.07) | 4.98 (4.71–5.31) | 4.81 (4.51–5.06)** | 5.04 (4.73–5.40) | 4.82 (4.56–5.20)** | 5.10 (4.78–5.45) | 4.91 (4.56–5.24)** | 5.27 (4.95–5.67) | 4.92 (4.54–5.22)** |
| TG (mmol/L) | 0.81 (0.64–1.12) | 0.72 (0.59–0.94)* | 1.35 (1.04–1.95) | 0.90 (0.71–1.34)** | 1.25 ± 0.80 | 1.04 ± 0.60** | 1.47 (1.03–2.12) | 1.22 (0.79–1.75)** | 1.39 (1.01–1.86) | 1.09 (0.81–1.45)** | 1.39 (0.99–1.82) | 1.13 (0.86–1.57)* |
| TCH (mmol/L) | 4.01 (3.63–4.56) | 4.19 (3.74–4.71)* | 4.21 (3.64–4.67) | 4.35 (3.88–4.84) | 4.39 ± 0.82 | 4.44 ± 0.72 | 4.45 (3.93–4.97) | 4.58 (3.95–5.12) | 4.84 (4.26–5.44) | 4.70 (4.27–5.35) | 4.63 (3.84–5.13) | 4.72 (4.08–5.24) |
| HDL-C (mmol/L) | 1.34 (1.14–1.51) | 1.52 (1.29–1.80)** | 1.02 (0.87–1.17) | 1.26 (1.09–1.50)** | 1.27 (1.09–1.52) | 1.41 (1.21–1.66)** | 1.03 (0.9–1.2) | 1.19 (1.00–1.39)** | 1.26 (1.08–1.46) | 1.40 (1.19–1.66)* | 1.12 (0.95–1.30) | 1.26 (1.07–1.45)* |
| LDL-C (mmol/L) | 2.2 (1.93–2.71) | 2.25 (1.88–2.67) | 2.53 (2.05–2.80) | 2.42 (2.17–2.78) | 2.52 ± 0.68 | 2.46 ± 0.58 | 2.64 (2.22–3.1) | 2.62 (2.14–3.10) | 2.86 (2.39–3.33) | 2.76 (2.28–3.28) | 2.70 (2.28–3.17) | 2.68 (2.18–3.11) |
| TSH (mIU/L) | 1.49 (1.10–2.12) | 1.48 (1.04–2.07) | 1.23 (0.89–1.78) | 1.66 (1.25–2.18)** | 1.41 (1.00–2.05) | 1.70 (1.18–2.23)** | 1.27 (0.96–1.71) | 1.49 (1.12–2.01)* | 1.42 (1.01–1.99) | 1.76 (1.24–2.63)** | 1.32 (0.67–1.95) | 1.51 (1.00–2.00) |
| TT4 (nmol/L) | 101.18 (90.10–111.41) | 96.76 (89.37–103.61)* | 102.12 (90.78–112.29) | 97.99 (85.69–107.37)* | 100.40 (90.72–109.74) | 94.79 (85.93–104.07)** | 98.91 (90.06–111.69) | 96.60 (85.44–105.40)* | 98.22 (88.28–110.76) | 101.26 (89.85–116.05) | 99.69 (87.78–111.69) | 90.82(81.32–102.80)* |
| TT3 (nmol/L) | 1.54 (1.39–1.69) | 1.52 (1.38–1.63) | 1.50 (1.38–1.62) | 1.62 (1.52–1.77)** | 1.53 (1.39–1.67) | 1.42 (1.30–1.56)** | 1.52 (1.38–1.66) | 1.62 (1.46–1.77)** | 1.55 (1.41–1.70) | 1.54 (1.43–1.68) | 1.51 (1.31–1.66) | 1.58 (1.45–1.79)* |
| FT4 (pmol/L) | 12.97 (12.10–13.85) | 13.16 (12.30–13.87) | 13.39 (12.57–14.44) | 13.54 (12.63–14.63) | 12.91 (12.11–13.78) | 12.67 (11.85–13.36)* | 13.18 (12.16–14.18) | 12.85 (12.24–13.59)* | 12.80 (12.02–13.73) | 12.74 (12.00–13.78) | 13.06 (12.13–13.88) | 12.41 (11.44–13.44)* |
| FT3 (pmol/L) | 4.56 (4.19–4.87) | 4.65 (4.37–5.00) | 4.46 (4.10–4.81) | 4.89 (4.64–5.18)** | 4.47 (4.14–4.85) | 4.33 (4.04–4.68)** | 4.50 (4.15–4.82) | 4.80 (4.44–5.03)** | 4.48 (4.11–4.81) | 4.49 (4.16–4.79) | 4.60 (4.19–4.94) | 4.56 (4.29–4.84) |
Notes:
BMI, Body Mass Index; FBG, fasting blood glucose; TG, triglycerides; TCH, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TSH, thyroid stimulating hormone; TT4, total thyroid hormone; TT3, total triiodothyronine; FT4, free thyroid hormone; FT3, free triiodothyronine.
*
P < 0.05.
**
P < 0.001.