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. 2025 Jun 3;38(6):963–974. doi: 10.1021/acs.chemrestox.4c00506

2. Mixtures of Three Compound/Metals with Two or Three Known Human Carcinogens Frequently Found at U.S. Superfund Sites.

No. of Superfund Sites Mixtures of Three Compound/Metals
Mixtures of Three with Three Known Compound/Metal Human Carcinogens
496 Nickel compounds, Cadmium, Arsenic compounds
451 Benzene, Arsenic compounds, Trichloroethene
433 Benzene, Cadmium, Arsenic compounds
424 Nickel compounds, Benzene, Arsenic compounds
420 Benzene, Vinyl Chloride, Trichloroethene
414 Cadmium, Arsenic compounds, Trichloroethene
391 Nickel compounds, Arsenic compounds, Trichloroethene
389 Nickel compounds, Benzene, Cadmium
386 Vinyl Chloride, Arsenic compounds, Trichloroethene
385 Beryllium, Cadmium, Arsenic compounds
379 Nickel compounds, Beryllium, Arsenic compounds
379 Benzene, Cadmium, Trichloroethene
368 Benzene, Vinyl Chloride, Arsenic compounds
366 Nickel compounds, Beryllium, Cadmium
366 Nickel compounds, Cadmium, Trichloroethene
360 Nickel compounds, Benzene, Trichloroethene
328 Benzene, Beryllium, Arsenic compounds
321 Cadmium, Vinyl Chloride, Arsenic compounds
Mixtures of Three with Two Known Compound/Metal Human Carcinogens
611 Lead, Cadmium, Arsenic compounds
549 Nickel compounds, Lead, Arsenic compounds
518 Benzene, Lead, Arsenic compounds
517 Nickel compound, Lead, Cadmium
500 Tetrachloroethene, Benzene, Trichloroethene
478 Lead, Arsenic compounds, Trichloroethene
474 Tetrachloroethene, Arsenic compounds, Trichloroethene
461 Tetrachloroethene, Vinyl Chloride, Trichloroethene
455 Benzene, Lead, Cadmium
452 Benzene, Lead, Trichloroethene
433 Nickel compound, Benzene, Lead
433 Lead, Cadmium, Trichloroethene