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. 2025 May 27;17(5):e84906. doi: 10.7759/cureus.84906

Table 4. Comparison between FI and NEC groups, in changes of CBC at three time points (n=92).

1 Comparison was done using the independent t-test. 2 Comparison was done using the Mann-Whitney test

All data are expressed as mean ±SD except as indicated. * per microlit, ** x 109 per lit, *** gm per dL

CBC = Complete blood count; Hb = Hemoglobin; FI = Feeding intolerance; IQR = Interquartile range; NEC = Necrotizing enterocolitis; WBC = White blood count

Characteristics FI (n = 63) NEC (n=29) Statistical value P value
Change from baseline to onset of NEC/FI WBC*, Mean (±SD) 1690±6259 -2190±6352 t = -2.750 0.007 1
Platelet**, Mean (±SD) 39±98 15±116 t = -1.010 0.348 1
Absolute Monocyte Count*, Mean (±SD) 724±1338 -482±1401 t = -3.960 <0.001 1
Absolute Neutrophil count*, Mean (±SD) 213±4054 -561±3951 t = -0.858 0.393 1
Absolute Lymphocyte count*, median (IQR) 556 (-986 to 1830) -984 (-2325 to 1532) U = -1.479 0.137 2
Hb***, median (IQR) -0.8 (-1.7 to 0.8) -1 (-2.5 to 1.3) U = -0.179 0.765 2
Change from onset of NEC/FI to lab parameter afterwards WBC*, Mean (±SD) -543±5026 2607±8455 t = 2.229 0.028 1
Platelet**, Mean (±SD) 1±89 -3±108 t =-0.185 0.854 1
Absolute Monocyte Count*, Mean (±SD) -370±1517 467±1689 t = 2.372 0.020 1
Absolute Neutrophil Count*, Mean (±SD) -550±4274 -409±5721 t = 0.0132 0.895 1
Absolute Lymphocyte Count*, Median (IQR) 333 (-1582 to 1574) 828 (-1753 to 2354) U = -1.479 0.375 2
Hb***, Median (IQR) -0.7 (-1.9 to 0.7) -0.5 (-3 to 1.4) U = -0.336 0.737 2