Table 3.
The weighted hazard ratios of CMD-specific and all-cause mortality by the combined Gait-DSST groups.
| Variable | aDeath no. /total no. | HR (95% CI) | P for interaction | |||
|---|---|---|---|---|---|---|
| Crude | Model 1 | Model 2 | Model 3 | |||
| CMD Mortality | 587/2482 | |||||
| Gait-DSST | 0.184 | |||||
| Group 1 | 164/1057 | 1 (Ref) | 1 (Ref) | 1 (Ref) | 1 (Ref) | |
| Group 2 | 161/715 | 1.74 (1.33, 2.27) | 1.27 (0.93, 1.73) | 1.19 (0.87, 1.63) | 1.09 (0.81, 1.47) | |
| Group 3 | 71/191 | 2.92 (2.08, 4.10) | 2.33 (1.64, 3.31) | 2.01(1.41, 2.86) | 1.86 (1.29, 2.68) | |
| Group 4 | 191/519 | 2.88 (2.31, 3.58) | 1.75 (1.38, 2.23) | 1.58 (1.23, 2.03) | 1.40 (1.07, 1.83) | |
| All-Cause Mortality | 1627/2482 | |||||
| Gait-DSST | 0.032 | |||||
| Group 1 | 542/1057 | 1 (Ref) | 1 (Ref) | 1 (Ref) | 1 (Ref) | |
| Group 2 | 481/715 | 2.06 (1.84, 2.31) | 1.56 (1.39, 1.76) | 1.56 (1.39, 1.76) | 1.51 (1.35, 1.68) | |
| Group 3 | 159/191 | 2.70 (2.14, 3.40) | 2.03 (1.61, 2.56) | 1.81 (1.43, 2.29) | 1.72 (1.35, 2.18) | |
| Group 4 | 445/519 | 3.54 (2.94, 4.26) | 2.31 (1.97, 2.71) | 2.12 (1.77, 2.53) | 2.01 (1.69, 2.39) | |
Death and total number of participants are presented as unweighted number.
CMD, cardiometabolic disease; DSST, Digit Symbol Substitution Test, a cognitive test of processing speed; HR, hazard ratio; CI, confidence interval; Group 1: normal gait and high DSST; Group 2: normal gait and low DSST; Group 3: slow gait and high DSST; Group 4: slow gait and low DSST. Model 1 was adjusted for age, sex, education, poverty income ratio (PIR); Model 2 was additionally adjusted for physical activity, balance, smokers, alcohol use, C-reactive protein (CRP) and history of cancer; Model 3 was further adjusted for the history of cardiovascular and cerebrovascular diseases (CVD) and cardiometabolic disease risk factors (CMDRF).