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. 2025 Jun 27;51(1):243. doi: 10.1007/s00068-025-02900-z

Table 5.

Sensitivity, specificity, positive and negative predictive values, accuracy by diagnostic method and their combinations (Based on patients n = 200)

Sensitivity (%) Specificity (%) Positive predictive value (%) Negative predictive value (%) Accuracy (%) Confidence intervall (of accuracy)
Standard culture 79.2 76.6 65.5 86.7 77.5 71.7–83.3
Sonication (overall) 80.6 74.2 63.7 87.2 76.5 70.6–82.4
Sonication conventional 56.9 85.9 69.5 78.0 75.5 69.5–81.5
Sonication with membrane filtration 79.2 78.9 67,9 85,7 78.0 72.3–83.7
Tissue homogenization 73.6 89.1 79.1 85.7 84.5 79.5–89.5
Histology 33.3 100 100 72.7 76.0 70.1–81.9
Standard culture and histology 88.9 76.6 68.1 92.5 81.0 75.6–86.4
Sonication and histology 90.3 74.2 66.3 93.1 80.0 74.5–85.5
Tissue homogenization and histology 90.3 89.1 82.3 94.2 89.5 85.3–93.7
Standard culture and sonication 97.2 57.8 56.5 97.4 72.0 65.8–78.2
Standard culture and tissue homogenization 93.1 68.0 62.0 94.6 77.0 71.2–82.8