Table 4.
Study of release profile of bisphosphonated Ca-based drug delivery systems
| Carrier composition | Bisphosphonate name | Cumulative drug release profile | Ref. |
|---|---|---|---|
| HAp | Alendronate | >90 % in 3 h (pH not specified) | [28] |
| CP | Alendronate | >90 % in 3 h (pH 4.7) | [29] |
| BG | Alendronate | >65 % in 48 h (pH 4.5) | [30] |
| Calcium Ion | Risedronate | >100 % in 48 h (pH 5.5) | [31] |
| HAp | Medronate | >100 % in 48 h (pH not specified) | [32] |
| CP | Medronate | >100 % in 48 h (pH not specified) | [32] |